Multidrug Resistant Pseudomonas Mycotic Pseudoaneurysm following Cardiac Transplant Bridged by Ventricular Assistant Device

Mycotic pseudoaneurysm of aorta following cardiac surgery is rare but is highly fatal if it is unrecognized and untreated. Here, we report a case of a 45-year-old male patient who presented with rapidly progressive multiple pseudoaneurysms of the ascending aorta infected with multidrug resistant (MD...

Full description

Saved in:
Bibliographic Details
Main Authors: C. Aye, M. Williams, R. Horvath
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Infectious Diseases
Online Access:http://dx.doi.org/10.1155/2017/1402320
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832566130727714816
author C. Aye
M. Williams
R. Horvath
author_facet C. Aye
M. Williams
R. Horvath
author_sort C. Aye
collection DOAJ
description Mycotic pseudoaneurysm of aorta following cardiac surgery is rare but is highly fatal if it is unrecognized and untreated. Here, we report a case of a 45-year-old male patient who presented with rapidly progressive multiple pseudoaneurysms of the ascending aorta infected with multidrug resistant (MDR) Pseudomonas aeruginosa at 5 weeks after cardiac transplantation, on a background of prior bridging therapy with left ventricular assistant device (LVAD). The patient was successfully treated with the newer cephalosporin, Ceftolozane/Tazobactam, in combination with surgery. This is the first reported case of mycotic pseudoaneurysm infected with MDR Pseudomonas. This case also highlights the importance of high vigilance and timely multimodality treatment in the diagnosis and management of mycotic pseudoaneurysm following cardiac transplant, especially in patients who had LVAD.
format Article
id doaj-art-5e8833f7e0dc454babe11591934cbe3d
institution Kabale University
issn 2090-6625
2090-6633
language English
publishDate 2017-01-01
publisher Wiley
record_format Article
series Case Reports in Infectious Diseases
spelling doaj-art-5e8833f7e0dc454babe11591934cbe3d2025-02-03T01:04:57ZengWileyCase Reports in Infectious Diseases2090-66252090-66332017-01-01201710.1155/2017/14023201402320Multidrug Resistant Pseudomonas Mycotic Pseudoaneurysm following Cardiac Transplant Bridged by Ventricular Assistant DeviceC. Aye0M. Williams1R. Horvath2Infection Management Unit, The Prince Charles Hospital, Brisbane, QLD 4032, AustraliaDepartment of Pharmacy, The Prince Charles Hospital, Brisbane, QLD 4032, AustraliaInfection Management Unit, The Prince Charles Hospital, Brisbane, QLD 4032, AustraliaMycotic pseudoaneurysm of aorta following cardiac surgery is rare but is highly fatal if it is unrecognized and untreated. Here, we report a case of a 45-year-old male patient who presented with rapidly progressive multiple pseudoaneurysms of the ascending aorta infected with multidrug resistant (MDR) Pseudomonas aeruginosa at 5 weeks after cardiac transplantation, on a background of prior bridging therapy with left ventricular assistant device (LVAD). The patient was successfully treated with the newer cephalosporin, Ceftolozane/Tazobactam, in combination with surgery. This is the first reported case of mycotic pseudoaneurysm infected with MDR Pseudomonas. This case also highlights the importance of high vigilance and timely multimodality treatment in the diagnosis and management of mycotic pseudoaneurysm following cardiac transplant, especially in patients who had LVAD.http://dx.doi.org/10.1155/2017/1402320
spellingShingle C. Aye
M. Williams
R. Horvath
Multidrug Resistant Pseudomonas Mycotic Pseudoaneurysm following Cardiac Transplant Bridged by Ventricular Assistant Device
Case Reports in Infectious Diseases
title Multidrug Resistant Pseudomonas Mycotic Pseudoaneurysm following Cardiac Transplant Bridged by Ventricular Assistant Device
title_full Multidrug Resistant Pseudomonas Mycotic Pseudoaneurysm following Cardiac Transplant Bridged by Ventricular Assistant Device
title_fullStr Multidrug Resistant Pseudomonas Mycotic Pseudoaneurysm following Cardiac Transplant Bridged by Ventricular Assistant Device
title_full_unstemmed Multidrug Resistant Pseudomonas Mycotic Pseudoaneurysm following Cardiac Transplant Bridged by Ventricular Assistant Device
title_short Multidrug Resistant Pseudomonas Mycotic Pseudoaneurysm following Cardiac Transplant Bridged by Ventricular Assistant Device
title_sort multidrug resistant pseudomonas mycotic pseudoaneurysm following cardiac transplant bridged by ventricular assistant device
url http://dx.doi.org/10.1155/2017/1402320
work_keys_str_mv AT caye multidrugresistantpseudomonasmycoticpseudoaneurysmfollowingcardiactransplantbridgedbyventricularassistantdevice
AT mwilliams multidrugresistantpseudomonasmycoticpseudoaneurysmfollowingcardiactransplantbridgedbyventricularassistantdevice
AT rhorvath multidrugresistantpseudomonasmycoticpseudoaneurysmfollowingcardiactransplantbridgedbyventricularassistantdevice