Piperine Alleviates Doxorubicin-Induced Cardiotoxicity via Activating PPAR-γ in Mice
Background. Oxidative stress, inflammation and cardiac apoptosis were closely involved in doxorubicin (DOX)-induced cardiac injury. Piperine has been reported to suppress inflammatory response and pyroptosis in macrophages. However, whether piperine could protect the mice against DOX-related cardiac...
Saved in:
Main Authors: | Jie Yan, Si-Chi Xu, Chun-Yan Kong, Xiao-Yang Zhou, Zhou-Yan Bian, Ling Yan, Qi-Zhu Tang |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2019-01-01
|
Series: | PPAR Research |
Online Access: | http://dx.doi.org/10.1155/2019/2601408 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
IFN-γ reprograms cardiac microvascular endothelial cells to mediate doxorubicin transport and influences the sensitivity of mice to doxorubicin-induced cardiotoxicity
by: Haoyu Ji, et al.
Published: (2025-01-01) -
Investigation of the efficacy of tyrosol on doxorubicin-induced acute cardiotoxicity in rats
by: Mustafa Cellat, et al.
Published: (2022-09-01) -
HuoXueTongFu Formula Alleviates Intraperitoneal Adhesion by Regulating Macrophage Polarization and the SOCS/JAK2/STAT/PPAR-γ Signalling Pathway
by: Min Zhao, et al.
Published: (2019-01-01) -
Identifying common pathways for doxorubicin and carfilzomib-induced cardiotoxicities: transcriptomic and epigenetic profiling
by: Conagh Kelly, et al.
Published: (2025-02-01) -
Methyl Gallate Attenuates Doxorubicin-Induced Cardiotoxicity in Rats by Suppressing Oxidative Stress
by: Akheruz Zaman Ahmed, et al.
Published: (2021-01-01)