Gorlin-Goltz Syndrome
The Gorlin-Goltz syndrome (GGS) (the nevoid basal cell carcinoma syndrome—NBCCS) is a rare autosomal dominant syndrome caused due to mutations in the PTCH (patched) gene found on chromosome arm 9q. The syndrome, characterized by increased predisposition to develop basal cell carcinoma and associated...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2012-01-01
|
| Series: | Case Reports in Dentistry |
| Online Access: | http://dx.doi.org/10.1155/2012/247239 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832556817019830272 |
|---|---|
| author | Padma Pandeshwar K. Jayanthi D. Mahesh |
| author_facet | Padma Pandeshwar K. Jayanthi D. Mahesh |
| author_sort | Padma Pandeshwar |
| collection | DOAJ |
| description | The Gorlin-Goltz syndrome (GGS) (the nevoid basal cell carcinoma syndrome—NBCCS) is a rare autosomal dominant syndrome caused due to mutations in the PTCH (patched) gene found on chromosome arm 9q. The syndrome, characterized by increased predisposition to develop basal cell carcinoma and associated multiorgan anomalies, has a high level of penetrance and variable expressiveness. GGS is a multidisciplinary problem, early diagnosis of which allows introduction of secondary prophylaxis and following an appropriate treatment to delay the progress of the syndrome. The following report emphasizes the need for awareness of the diagnostic criteria of this syndrome in cases with no typical skin lesions. |
| format | Article |
| id | doaj-art-5e69216ce271483da9cf21501d2da408 |
| institution | Kabale University |
| issn | 2090-6447 2090-6455 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Dentistry |
| spelling | doaj-art-5e69216ce271483da9cf21501d2da4082025-02-03T05:44:17ZengWileyCase Reports in Dentistry2090-64472090-64552012-01-01201210.1155/2012/247239247239Gorlin-Goltz SyndromePadma Pandeshwar0K. Jayanthi1D. Mahesh2Sri Venkateshwara Dental College and Hospital, Kariyappanahalli, Anekal Road, Bannerughatta, Bangalore 560083, IndiaOral Medicine, Diagnosis and Radiology, Bangalore Institute of Dental Sciences, Lakkasandra, Wilson Garden, Bangalore, IndiaDayananda Sagar College of Dental Sciences, Shivage Malleshwara Hills, Kumarswamy Layout, Bangalore, IndiaThe Gorlin-Goltz syndrome (GGS) (the nevoid basal cell carcinoma syndrome—NBCCS) is a rare autosomal dominant syndrome caused due to mutations in the PTCH (patched) gene found on chromosome arm 9q. The syndrome, characterized by increased predisposition to develop basal cell carcinoma and associated multiorgan anomalies, has a high level of penetrance and variable expressiveness. GGS is a multidisciplinary problem, early diagnosis of which allows introduction of secondary prophylaxis and following an appropriate treatment to delay the progress of the syndrome. The following report emphasizes the need for awareness of the diagnostic criteria of this syndrome in cases with no typical skin lesions.http://dx.doi.org/10.1155/2012/247239 |
| spellingShingle | Padma Pandeshwar K. Jayanthi D. Mahesh Gorlin-Goltz Syndrome Case Reports in Dentistry |
| title | Gorlin-Goltz Syndrome |
| title_full | Gorlin-Goltz Syndrome |
| title_fullStr | Gorlin-Goltz Syndrome |
| title_full_unstemmed | Gorlin-Goltz Syndrome |
| title_short | Gorlin-Goltz Syndrome |
| title_sort | gorlin goltz syndrome |
| url | http://dx.doi.org/10.1155/2012/247239 |
| work_keys_str_mv | AT padmapandeshwar gorlingoltzsyndrome AT kjayanthi gorlingoltzsyndrome AT dmahesh gorlingoltzsyndrome |