A Case for Doxycycline as an Effective Treatment for Confluent and Reticulated Papillomatosis (CARP)

Confluent and reticulated papillomatosis (CARP) is a rare keratinization disorder that presents with asymptomatic, reticulated papules coalescing into plaques, which adversely affect, most often, young black persons. Minocycline is considered the drug of choice, but it is not without its host of pot...

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Main Authors: Aishwarya Sharma, Deborah Moon, Dong Joo Kim
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Case Reports in Dermatological Medicine
Online Access:http://dx.doi.org/10.1155/2023/6397272
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author Aishwarya Sharma
Deborah Moon
Dong Joo Kim
author_facet Aishwarya Sharma
Deborah Moon
Dong Joo Kim
author_sort Aishwarya Sharma
collection DOAJ
description Confluent and reticulated papillomatosis (CARP) is a rare keratinization disorder that presents with asymptomatic, reticulated papules coalescing into plaques, which adversely affect, most often, young black persons. Minocycline is considered the drug of choice, but it is not without its host of potential side effects, including drug hypersensitivity, drug-induced lupus/vasculitis/hepatitis, blue-gray skin hyperpigmentation, acute eosinophilic pneumonia, pseudotumor cerebri, and vestibular instability, among others. Alternatively, doxycycline might be considered as another first-line agent for CARP as it can effectively clear lesions while offering a more favorable side effect profile in select patients. Herein, we present a case of CARP successfully resolved with doxycycline after a protracted treatment history of topical and oral antifungal medications for suspected tinea versicolor (TV).
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spelling doaj-art-5e6709c5d130445bb7b1374fe49a6ef52025-02-03T05:44:35ZengWileyCase Reports in Dermatological Medicine2090-64712023-01-01202310.1155/2023/6397272A Case for Doxycycline as an Effective Treatment for Confluent and Reticulated Papillomatosis (CARP)Aishwarya Sharma0Deborah Moon1Dong Joo Kim2School of Medicine and Health SciencesDepartment of DermatologyDepartment of Internal MedicineConfluent and reticulated papillomatosis (CARP) is a rare keratinization disorder that presents with asymptomatic, reticulated papules coalescing into plaques, which adversely affect, most often, young black persons. Minocycline is considered the drug of choice, but it is not without its host of potential side effects, including drug hypersensitivity, drug-induced lupus/vasculitis/hepatitis, blue-gray skin hyperpigmentation, acute eosinophilic pneumonia, pseudotumor cerebri, and vestibular instability, among others. Alternatively, doxycycline might be considered as another first-line agent for CARP as it can effectively clear lesions while offering a more favorable side effect profile in select patients. Herein, we present a case of CARP successfully resolved with doxycycline after a protracted treatment history of topical and oral antifungal medications for suspected tinea versicolor (TV).http://dx.doi.org/10.1155/2023/6397272
spellingShingle Aishwarya Sharma
Deborah Moon
Dong Joo Kim
A Case for Doxycycline as an Effective Treatment for Confluent and Reticulated Papillomatosis (CARP)
Case Reports in Dermatological Medicine
title A Case for Doxycycline as an Effective Treatment for Confluent and Reticulated Papillomatosis (CARP)
title_full A Case for Doxycycline as an Effective Treatment for Confluent and Reticulated Papillomatosis (CARP)
title_fullStr A Case for Doxycycline as an Effective Treatment for Confluent and Reticulated Papillomatosis (CARP)
title_full_unstemmed A Case for Doxycycline as an Effective Treatment for Confluent and Reticulated Papillomatosis (CARP)
title_short A Case for Doxycycline as an Effective Treatment for Confluent and Reticulated Papillomatosis (CARP)
title_sort case for doxycycline as an effective treatment for confluent and reticulated papillomatosis carp
url http://dx.doi.org/10.1155/2023/6397272
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