Identification of subgroups of self-reported outcomes among breast cancer patients undergoing surgery and chemotherapy: A cross-sectional study
Objectives: To identify the subgroups of self-reported outcomes and associated factors among breast cancer patients undergoing surgery and chemotherapy. Methods: A cross-sectional study was conducted between January and November 2021. We recruited patients from two tertiary hospitals in Shanghai, Ch...
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Elsevier
2025-01-01
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| Series: | International Journal of Nursing Sciences |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352013224001303 |
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| author | Feixia Ni Tingting Cai Tingting Zhou Changrong Yuan |
| author_facet | Feixia Ni Tingting Cai Tingting Zhou Changrong Yuan |
| author_sort | Feixia Ni |
| collection | DOAJ |
| description | Objectives: To identify the subgroups of self-reported outcomes and associated factors among breast cancer patients undergoing surgery and chemotherapy. Methods: A cross-sectional study was conducted between January and November 2021. We recruited patients from two tertiary hospitals in Shanghai, China, using convenience sampling during their hospitalization. Patients were assessed using a questionnaire that included sociodemographic and clinical characteristics, the Patient Reported Outcomes Measurement Information System profile-29 (PROMIS-29), and the PROMIS-cognitive function short form 4a. Latent class analysis was performed to examine possible classes regarding self-reported outcomes. Multiple logistic regression analysis was used to determine the associated factors. Analysis of variance (ANOVA) was conducted for symptoms across the different classes. Results: A total of 640 patients participated in this study. The findings revealed three subgroups in terms of self-reported outcomes among breast cancer patients undergoing surgery and chemotherapy: low physical-social-cognitive function, high physical-low cognitive function, and high physical-social-cognitive function. Multivariable logistic regression analysis showed that age (≥ 60 years old), menopause, the third chemotherapy cycle, undergoing simple mastectomy and breast reconstruction, duration of disease 3–12 months, stage III/IV cancer, and severe pain were associated factors of the functional decline groups. Besides, significant differences in depression and sleep disorders were observed among the three groups. Conclusions: Breast cancer patients receiving surgery and chemotherapy can be divided into three subgroups. Aging, menopause, chemotherapy cycle, surgery type, duration and stage of disease, and severe pain affected the functional decline groups. Consequently, healthcare professionals should make tailored interventions to address the specific functional rehabilitation and symptom relief needs. |
| format | Article |
| id | doaj-art-5e4a65db772b400c966410da59664321 |
| institution | Kabale University |
| issn | 2352-0132 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | International Journal of Nursing Sciences |
| spelling | doaj-art-5e4a65db772b400c966410da596643212025-01-26T05:04:00ZengElsevierInternational Journal of Nursing Sciences2352-01322025-01-011215158Identification of subgroups of self-reported outcomes among breast cancer patients undergoing surgery and chemotherapy: A cross-sectional studyFeixia Ni0Tingting Cai1Tingting Zhou2Changrong Yuan3Department of Pediatric Hematology/Oncology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China; School of Nursing, Fudan University, Shanghai, ChinaSchool of Nursing, Fudan University, Shanghai, ChinaSchool of Nursing, Fudan University, Shanghai, ChinaSchool of Nursing, Fudan University, Shanghai, China; Corresponding author.Objectives: To identify the subgroups of self-reported outcomes and associated factors among breast cancer patients undergoing surgery and chemotherapy. Methods: A cross-sectional study was conducted between January and November 2021. We recruited patients from two tertiary hospitals in Shanghai, China, using convenience sampling during their hospitalization. Patients were assessed using a questionnaire that included sociodemographic and clinical characteristics, the Patient Reported Outcomes Measurement Information System profile-29 (PROMIS-29), and the PROMIS-cognitive function short form 4a. Latent class analysis was performed to examine possible classes regarding self-reported outcomes. Multiple logistic regression analysis was used to determine the associated factors. Analysis of variance (ANOVA) was conducted for symptoms across the different classes. Results: A total of 640 patients participated in this study. The findings revealed three subgroups in terms of self-reported outcomes among breast cancer patients undergoing surgery and chemotherapy: low physical-social-cognitive function, high physical-low cognitive function, and high physical-social-cognitive function. Multivariable logistic regression analysis showed that age (≥ 60 years old), menopause, the third chemotherapy cycle, undergoing simple mastectomy and breast reconstruction, duration of disease 3–12 months, stage III/IV cancer, and severe pain were associated factors of the functional decline groups. Besides, significant differences in depression and sleep disorders were observed among the three groups. Conclusions: Breast cancer patients receiving surgery and chemotherapy can be divided into three subgroups. Aging, menopause, chemotherapy cycle, surgery type, duration and stage of disease, and severe pain affected the functional decline groups. Consequently, healthcare professionals should make tailored interventions to address the specific functional rehabilitation and symptom relief needs.http://www.sciencedirect.com/science/article/pii/S2352013224001303Breast neoplasmsLatent class analysisFunctionSurgeryChemotherapy |
| spellingShingle | Feixia Ni Tingting Cai Tingting Zhou Changrong Yuan Identification of subgroups of self-reported outcomes among breast cancer patients undergoing surgery and chemotherapy: A cross-sectional study International Journal of Nursing Sciences Breast neoplasms Latent class analysis Function Surgery Chemotherapy |
| title | Identification of subgroups of self-reported outcomes among breast cancer patients undergoing surgery and chemotherapy: A cross-sectional study |
| title_full | Identification of subgroups of self-reported outcomes among breast cancer patients undergoing surgery and chemotherapy: A cross-sectional study |
| title_fullStr | Identification of subgroups of self-reported outcomes among breast cancer patients undergoing surgery and chemotherapy: A cross-sectional study |
| title_full_unstemmed | Identification of subgroups of self-reported outcomes among breast cancer patients undergoing surgery and chemotherapy: A cross-sectional study |
| title_short | Identification of subgroups of self-reported outcomes among breast cancer patients undergoing surgery and chemotherapy: A cross-sectional study |
| title_sort | identification of subgroups of self reported outcomes among breast cancer patients undergoing surgery and chemotherapy a cross sectional study |
| topic | Breast neoplasms Latent class analysis Function Surgery Chemotherapy |
| url | http://www.sciencedirect.com/science/article/pii/S2352013224001303 |
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