Microbiologic Spectrum and Antibiotic Susceptibility Pattern among Patients with Urinary and Respiratory Tract Infection
Aim. To demonstrate the prevalence of isolated organisms in urinary/respiratory tract infections and their antibiotic susceptibilities in a tertiary care center. Methods and Material. Between January 2008 and January 2010, patients referring to the clinic of cardiology or those admitted to the cardi...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | International Journal of Microbiology |
| Online Access: | http://dx.doi.org/10.1155/2014/682304 |
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| author | Maryam Sotoudeh Anvari Mohammad Naderan Mohammad Ali Boroumand Saeed Shoar Robab Bakhshi Morteza Naderan |
| author_facet | Maryam Sotoudeh Anvari Mohammad Naderan Mohammad Ali Boroumand Saeed Shoar Robab Bakhshi Morteza Naderan |
| author_sort | Maryam Sotoudeh Anvari |
| collection | DOAJ |
| description | Aim. To demonstrate the prevalence of isolated organisms in urinary/respiratory tract infections and their antibiotic susceptibilities in a tertiary care center. Methods and Material. Between January 2008 and January 2010, patients referring to the clinic of cardiology or those admitted to the cardiac wards were enrolled in this cross-sectional descriptive study. Urine and sputum sampling was done for all the patients and the specimens underwent microbiologic examination and, in case of isolation of microorganism, antibiotic disk diffusion test was performed. Results. Escherichia coli (E. coli) was the most prevalent isolated organism in-hospital and community-acquired UTIs and was highly resistant to cephalothin in all the samples followed by cotrimoxazole, and ceftriaxone. It revealed high sensitivity to imipenem, amikacin, and nitrofurantoin. Acinetobacter constituted the most prevalent organism isolated from respiratory secretions and represented the highest resistance to ceftriaxone and the greatest sensitivity to imipenem. Conclusions. E. coli and Acinetobacter remain the most common uropathogenic and respiratory organisms, respectively. However, their increasing resistance to wide-spectrum imipenem, meropenem, and vancomycin is a major concern. |
| format | Article |
| id | doaj-art-5e460a996306458b8483969e38c33811 |
| institution | Kabale University |
| issn | 1687-918X 1687-9198 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Microbiology |
| spelling | doaj-art-5e460a996306458b8483969e38c338112025-02-03T06:00:14ZengWileyInternational Journal of Microbiology1687-918X1687-91982014-01-01201410.1155/2014/682304682304Microbiologic Spectrum and Antibiotic Susceptibility Pattern among Patients with Urinary and Respiratory Tract InfectionMaryam Sotoudeh Anvari0Mohammad Naderan1Mohammad Ali Boroumand2Saeed Shoar3Robab Bakhshi4Morteza Naderan5Department of Surgical and Clinical Pathology, Tehran Heart Center, Tehran University of Medical Sciences, Tehran 1411713138, IranDepartment of Surgical and Clinical Pathology, Tehran Heart Center, Tehran University of Medical Sciences, Tehran 1411713138, IranDepartment of Surgical and Clinical Pathology, Tehran Heart Center, Tehran University of Medical Sciences, Tehran 1411713138, IranDepartment of Surgical and Clinical Pathology, Tehran Heart Center, Tehran University of Medical Sciences, Tehran 1411713138, IranDepartment of Research, Tehran Heart Center, Tehran University of Medical Sciences, North Karegar Avenue, Tehran 1411713138, IranDepartment of Research, Tehran Heart Center, Tehran University of Medical Sciences, North Karegar Avenue, Tehran 1411713138, IranAim. To demonstrate the prevalence of isolated organisms in urinary/respiratory tract infections and their antibiotic susceptibilities in a tertiary care center. Methods and Material. Between January 2008 and January 2010, patients referring to the clinic of cardiology or those admitted to the cardiac wards were enrolled in this cross-sectional descriptive study. Urine and sputum sampling was done for all the patients and the specimens underwent microbiologic examination and, in case of isolation of microorganism, antibiotic disk diffusion test was performed. Results. Escherichia coli (E. coli) was the most prevalent isolated organism in-hospital and community-acquired UTIs and was highly resistant to cephalothin in all the samples followed by cotrimoxazole, and ceftriaxone. It revealed high sensitivity to imipenem, amikacin, and nitrofurantoin. Acinetobacter constituted the most prevalent organism isolated from respiratory secretions and represented the highest resistance to ceftriaxone and the greatest sensitivity to imipenem. Conclusions. E. coli and Acinetobacter remain the most common uropathogenic and respiratory organisms, respectively. However, their increasing resistance to wide-spectrum imipenem, meropenem, and vancomycin is a major concern.http://dx.doi.org/10.1155/2014/682304 |
| spellingShingle | Maryam Sotoudeh Anvari Mohammad Naderan Mohammad Ali Boroumand Saeed Shoar Robab Bakhshi Morteza Naderan Microbiologic Spectrum and Antibiotic Susceptibility Pattern among Patients with Urinary and Respiratory Tract Infection International Journal of Microbiology |
| title | Microbiologic Spectrum and Antibiotic Susceptibility Pattern among Patients with Urinary and Respiratory Tract Infection |
| title_full | Microbiologic Spectrum and Antibiotic Susceptibility Pattern among Patients with Urinary and Respiratory Tract Infection |
| title_fullStr | Microbiologic Spectrum and Antibiotic Susceptibility Pattern among Patients with Urinary and Respiratory Tract Infection |
| title_full_unstemmed | Microbiologic Spectrum and Antibiotic Susceptibility Pattern among Patients with Urinary and Respiratory Tract Infection |
| title_short | Microbiologic Spectrum and Antibiotic Susceptibility Pattern among Patients with Urinary and Respiratory Tract Infection |
| title_sort | microbiologic spectrum and antibiotic susceptibility pattern among patients with urinary and respiratory tract infection |
| url | http://dx.doi.org/10.1155/2014/682304 |
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