A novel peptide inhibitor of TRPM2 channels improves recovery of memory function following traumatic brain injury

A novel peptide inhibitor of TRPM2 channels improves recovery of memory function following traumatic brain injury

Traumatic Brain Injury (TBI) is a leading cause of mortality and morbidity in adults and can lead to long-term disability, including cognitive and motor deficits. Despite advances in research, there are currently no pharmacological interventions to improve outcomes after TBI. Studies suggest that no...

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Bibliographic Details
Main Authors: James E. Orfila, Robert M. Dietz, Christian Schroeder, Olivia P. Patsos, Amelia Burch, Kiara E. Bahamonde, Kelley A. Coakley, Danelle J. Carter, Amy C. Clevenger, Tara B. Hendry-Hofer, Tuan D. Le, Joseph K. Maddry, Steven G. Schauer, Vikhyat S. Bebarta, Paco S. Herson
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
traumatic brain injury
neuroprotection
long-term potentiation
cognition
histology
Online Access:https://www.frontiersin.org/articles/10.3389/fnsyn.2025.1534379/full
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