Genetic determinants of serum testosterone concentrations in men.

Genetic determinants of serum testosterone concentrations in men.

Testosterone concentrations in men are associated with cardiovascular morbidity, osteoporosis, and mortality and are affected by age, smoking, and obesity. Because of serum testosterone's high heritability, we performed a meta-analysis of genome-wide association data in 8,938 men from seven coh...

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Main Authors: Claes Ohlsson, Henri Wallaschofski, Kathryn L Lunetta, Lisette Stolk, John R B Perry, Annemarie Koster, Ann-Kristin Petersen, Joel Eriksson, Terho Lehtimäki, Ilpo T Huhtaniemi, Geoffrey L Hammond, Marcello Maggio, Andrea D Coviello, EMAS Study Group, Luigi Ferrucci, Margit Heier, Albert Hofman, Kate L Holliday, John-Olov Jansson, Mika Kähönen, David Karasik, Magnus K Karlsson, Douglas P Kiel, Yongmei Liu, Osten Ljunggren, Mattias Lorentzon, Leo-Pekka Lyytikäinen, Thomas Meitinger, Dan Mellström, David Melzer, Iva Miljkovic, Matthias Nauck, Maria Nilsson, Brenda Penninx, Stephen R Pye, Ramachandran S Vasan, Martin Reincke, Fernando Rivadeneira, Abdelouahid Tajar, Alexander Teumer, André G Uitterlinden, Jagadish Ulloor, Jorma Viikari, Uwe Völker, Henry Völzke, H Erich Wichmann, Tsung-Sheng Wu, Wei Vivian Zhuang, Elad Ziv, Frederick C W Wu, Olli Raitakari, Anna Eriksson, Martin Bidlingmaier, Tamara B Harris, Anna Murray, Frank H de Jong, Joanne M Murabito, Shalender Bhasin, Liesbeth Vandenput, Robin Haring
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-10-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1002313&type=printable
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