Women Are More Susceptible to Caries but Individuals Born with Clefts Are Not
The identification of individuals at a higher risk of developing caries is of great interest. Isolated forms of cleft lip and palate are among the most common craniofacial congenital anomalies in humans. Historically, several reports suggest that individuals born with clefts have a higher risk for c...
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| Main Authors: | , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | International Journal of Dentistry |
| Online Access: | http://dx.doi.org/10.1155/2011/454532 |
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| author | Aditi Jindal Michelle McMeans Somnya Narayanan Erin K. Rose Shilpa Jain Mary L. Marazita Renato Menezes Ariadne Letra Flavia M. Carvalho Carla A. Brandon Judith M. Resick Juan C. Mereb Fernando A. Poletta Jorge S. Lopez-Camelo Eduardo E. Castilla Iêda M. Orioli Alexandre R. Vieira |
| author_facet | Aditi Jindal Michelle McMeans Somnya Narayanan Erin K. Rose Shilpa Jain Mary L. Marazita Renato Menezes Ariadne Letra Flavia M. Carvalho Carla A. Brandon Judith M. Resick Juan C. Mereb Fernando A. Poletta Jorge S. Lopez-Camelo Eduardo E. Castilla Iêda M. Orioli Alexandre R. Vieira |
| author_sort | Aditi Jindal |
| collection | DOAJ |
| description | The identification of individuals at a higher risk of developing caries is of great interest. Isolated forms of cleft lip and palate are among the most common craniofacial congenital anomalies in humans. Historically, several reports suggest that individuals born with clefts have a higher risk for caries. Caries continues to be the most common infectious noncontagious disease worldwide and a great burden to any health system. The identification of individuals of higher susceptibility to caries is of great interest. In this paper, we assessed caries experience of 1,593 individuals from three distinct populations. The study included individuals born with clefts, their unaffected relatives, and unrelated unaffected controls that were recruited from areas with similar cultural pressures and limited access to dental care. DMFT/dmft scores were obtained, and caries experience rates were compared among the three groups in each geographic area. Individuals born with clefts did not present higher caries experience in comparison to their unaffected relatives or unrelated unaffected controls. Women tend to present higher caries rates in comparison to men. Our work provides strong evidence that individuals born with clefts are not at higher risk to caries; however, women tend to have more severe caries experience. |
| format | Article |
| id | doaj-art-5e018c7df30248a6bbf5bf15decbca67 |
| institution | Kabale University |
| issn | 1687-8728 1687-8736 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Dentistry |
| spelling | doaj-art-5e018c7df30248a6bbf5bf15decbca672025-02-03T01:09:07ZengWileyInternational Journal of Dentistry1687-87281687-87362011-01-01201110.1155/2011/454532454532Women Are More Susceptible to Caries but Individuals Born with Clefts Are NotAditi Jindal0Michelle McMeans1Somnya Narayanan2Erin K. Rose3Shilpa Jain4Mary L. Marazita5Renato Menezes6Ariadne Letra7Flavia M. Carvalho8Carla A. Brandon9Judith M. Resick10Juan C. Mereb11Fernando A. Poletta12Jorge S. Lopez-Camelo13Eduardo E. Castilla14Iêda M. Orioli15Alexandre R. Vieira16Departments of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USADepartments of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USADepartments of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USADepartments of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USADivision of Pediatric Hematology-Oncology, Children’s Hospital of Pittsburgh, Pittsburgh, PA 15224, USADepartments of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USADepartments of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USADepartments of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USADepartment of Genetics, Center of Health Sciences, Institute of Biology, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, BrazilDepartments of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USADepartments of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA(ECLAMC) Latin American Collaborative Study of Congenital Malformations at Hospital de Area El Bolsón, Río Negro, Argentina(ECLAMC at CEMIC) Center for Medical Education and Clinical Research, Buenos Aires, Argentina(ECLAMC at CEMIC) Center for Medical Education and Clinical Research, Buenos Aires, Argentina(CONICET) National Research Council of Argentina, ArgentinaDepartment of Genetics, Center of Health Sciences, Institute of Biology, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, BrazilDepartments of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USAThe identification of individuals at a higher risk of developing caries is of great interest. Isolated forms of cleft lip and palate are among the most common craniofacial congenital anomalies in humans. Historically, several reports suggest that individuals born with clefts have a higher risk for caries. Caries continues to be the most common infectious noncontagious disease worldwide and a great burden to any health system. The identification of individuals of higher susceptibility to caries is of great interest. In this paper, we assessed caries experience of 1,593 individuals from three distinct populations. The study included individuals born with clefts, their unaffected relatives, and unrelated unaffected controls that were recruited from areas with similar cultural pressures and limited access to dental care. DMFT/dmft scores were obtained, and caries experience rates were compared among the three groups in each geographic area. Individuals born with clefts did not present higher caries experience in comparison to their unaffected relatives or unrelated unaffected controls. Women tend to present higher caries rates in comparison to men. Our work provides strong evidence that individuals born with clefts are not at higher risk to caries; however, women tend to have more severe caries experience.http://dx.doi.org/10.1155/2011/454532 |
| spellingShingle | Aditi Jindal Michelle McMeans Somnya Narayanan Erin K. Rose Shilpa Jain Mary L. Marazita Renato Menezes Ariadne Letra Flavia M. Carvalho Carla A. Brandon Judith M. Resick Juan C. Mereb Fernando A. Poletta Jorge S. Lopez-Camelo Eduardo E. Castilla Iêda M. Orioli Alexandre R. Vieira Women Are More Susceptible to Caries but Individuals Born with Clefts Are Not International Journal of Dentistry |
| title | Women Are More Susceptible to Caries but Individuals Born with Clefts Are Not |
| title_full | Women Are More Susceptible to Caries but Individuals Born with Clefts Are Not |
| title_fullStr | Women Are More Susceptible to Caries but Individuals Born with Clefts Are Not |
| title_full_unstemmed | Women Are More Susceptible to Caries but Individuals Born with Clefts Are Not |
| title_short | Women Are More Susceptible to Caries but Individuals Born with Clefts Are Not |
| title_sort | women are more susceptible to caries but individuals born with clefts are not |
| url | http://dx.doi.org/10.1155/2011/454532 |
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