Lung function impairment and eosinophilia in patients with eosinophilic chronic rhinosinusitis

Lung function impairment and eosinophilia in patients with eosinophilic chronic rhinosinusitis

Background: Eosinophilic chronic rhinosinusitis (ECRS) is characterized by intense eosinophil infiltration in nasal polyps (NPs), related to asthma comorbidity and elevated circulating eosinophil levels. The mechanism by which these systemic components affect type 2 inflammation in NPs is poorly und...

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Main Authors: Yuki Sonoda, MD, Yoshimasa Imoto, MD, PhD, Ayako Maegawa, MD, Anna Shimizu, MD, Masanori Kidoguchi, MD, PhD, Rikako Gozawa, MD, Keisuke Koyama, MD, Naoto Adachi, MD, Taiyo Morikawa, MD, PhD, Yuto Miyazaki, MD, Takahiro Tokunaga, MD, PhD, Masafumi Sakashita, MD, PhD, Shigeharu Ueki, MD, PhD, Takechiyo Yamada, MD, PhD, Shigeharu Fujieda, MD, PhD
Format: Article
Language:English
Published: Elsevier 2025-11-01
Series:Journal of Allergy and Clinical Immunology: Global
Subjects:
Eosinophilic chronic rhinosinusitis
lung function
eosinophils
type 2 cytokines
asthma
nasal polyps
Online Access:http://www.sciencedirect.com/science/article/pii/S2772829325001511
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