Dermal macrophages control tactile perception under physiological conditions via NGF signaling

Dermal macrophages control tactile perception under physiological conditions via NGF signaling

Abstract We demonstrated previously that sorting nexin 25 (SNX25) in nerve-associated macrophages plays critical roles in pain sensation by regulating tissue NGF content under both physiological and neuropathic conditions. In the present study, we apply the SNX25–NGF paradigm to tactile perception b...

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Bibliographic Details
Main Authors: Tatsuhide Tanaka, Ayami Isonishi, Mitsuko Banja, Rikuto Yamamoto, Masaki Sonobe, Emiko Okuda-Ashitaka, Hidemasa Furue, Hiroaki Okuda, Kouko Tatsumi, Akio Wanaka
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Dermal macrophage
Tactile perception
SNX25
NGF
Online Access:https://doi.org/10.1038/s41598-024-78683-x
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