Is There Any Association between PEEP and Upper Extremity DVT?
Background. We hypothesized that positive end-exploratory pressure (PEEP) may promote venous stasis in the upper extremities and predispose to upper extremity deep vein thrombosis (UEDVT). Methods. We performed a retrospective case control study of medical intensive care unit patients who required m...
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Wiley
2015-01-01
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| Series: | Critical Care Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2015/614598 |
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| author | Farah Al-Saffar Ena Gupta Furqan Siddiqi Muhammad Faisal Lisa M. Jones Vandana Seeram Mariam Louis James D. Cury Abubakr A. Bajwa Adil Shujaat |
| author_facet | Farah Al-Saffar Ena Gupta Furqan Siddiqi Muhammad Faisal Lisa M. Jones Vandana Seeram Mariam Louis James D. Cury Abubakr A. Bajwa Adil Shujaat |
| author_sort | Farah Al-Saffar |
| collection | DOAJ |
| description | Background. We hypothesized that positive end-exploratory pressure (PEEP) may promote venous stasis in the upper extremities and predispose to upper extremity deep vein thrombosis (UEDVT). Methods. We performed a retrospective case control study of medical intensive care unit patients who required mechanical ventilation (MV) for >72 hours and underwent duplex ultrasound of their upper veins for suspected DVT between January 2011 and December 2013. Results. UEDVT was found in 32 (28.5%) of 112 patients. Nineteen (67.8%) had a central venous catheter on the same side. The mean ± SD duration of MV was 13.2±9.5 days. Average PEEP was 7.13±2.97 cm H2O. Average PEEP was ≥10 cm H2O in 23 (20.5%) patients. Congestive heart failure (CHF) significantly increased the odds of UEDVT (OR 4.53, 95% CI 1.13–18.11; P=0.03) whereas longer duration of MV (≥13 vs. <13 days) significantly reduced it (OR 0.29, 95% CI 0.11–0.8; P=0.02). Morbid obesity showed a trend towards significance (OR 3.82, 95% CI 0.95–15.4; P=0.06). Neither PEEP nor any of the other analyzed predictors was associated with UEDVT. Conclusions. There is no association between PEEP and UEDVT. CHF may predispose to UEDVT whereas the risk of UEDVT declines with longer duration of MV. |
| format | Article |
| id | doaj-art-5db13acacea84971bb1ac950e19e8d70 |
| institution | Kabale University |
| issn | 2090-1305 2090-1313 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Critical Care Research and Practice |
| spelling | doaj-art-5db13acacea84971bb1ac950e19e8d702025-02-03T01:27:45ZengWileyCritical Care Research and Practice2090-13052090-13132015-01-01201510.1155/2015/614598614598Is There Any Association between PEEP and Upper Extremity DVT?Farah Al-Saffar0Ena Gupta1Furqan Siddiqi2Muhammad Faisal3Lisa M. Jones4Vandana Seeram5Mariam Louis6James D. Cury7Abubakr A. Bajwa8Adil Shujaat9Department of Medicine, University of Florida College of Medicine, Jacksonville, FL 32209, USADepartment of Medicine, University of Florida College of Medicine, Jacksonville, FL 32209, USADivision of Pulmonary, Critical Care and Sleep Medicine, University of Florida College of Medicine, Jacksonville, FL 32209, USADivision of Pulmonary, Critical Care and Sleep Medicine, University of Florida College of Medicine, Jacksonville, FL 32209, USADivision of Pulmonary, Critical Care and Sleep Medicine, University of Florida College of Medicine, Jacksonville, FL 32209, USADivision of Pulmonary, Critical Care and Sleep Medicine, University of Florida College of Medicine, Jacksonville, FL 32209, USADivision of Pulmonary, Critical Care and Sleep Medicine, University of Florida College of Medicine, Jacksonville, FL 32209, USADivision of Pulmonary, Critical Care and Sleep Medicine, University of Florida College of Medicine, Jacksonville, FL 32209, USADivision of Pulmonary, Critical Care and Sleep Medicine, University of Florida College of Medicine, Jacksonville, FL 32209, USADivision of Pulmonary, Critical Care and Sleep Medicine, University of Florida College of Medicine, Jacksonville, FL 32209, USABackground. We hypothesized that positive end-exploratory pressure (PEEP) may promote venous stasis in the upper extremities and predispose to upper extremity deep vein thrombosis (UEDVT). Methods. We performed a retrospective case control study of medical intensive care unit patients who required mechanical ventilation (MV) for >72 hours and underwent duplex ultrasound of their upper veins for suspected DVT between January 2011 and December 2013. Results. UEDVT was found in 32 (28.5%) of 112 patients. Nineteen (67.8%) had a central venous catheter on the same side. The mean ± SD duration of MV was 13.2±9.5 days. Average PEEP was 7.13±2.97 cm H2O. Average PEEP was ≥10 cm H2O in 23 (20.5%) patients. Congestive heart failure (CHF) significantly increased the odds of UEDVT (OR 4.53, 95% CI 1.13–18.11; P=0.03) whereas longer duration of MV (≥13 vs. <13 days) significantly reduced it (OR 0.29, 95% CI 0.11–0.8; P=0.02). Morbid obesity showed a trend towards significance (OR 3.82, 95% CI 0.95–15.4; P=0.06). Neither PEEP nor any of the other analyzed predictors was associated with UEDVT. Conclusions. There is no association between PEEP and UEDVT. CHF may predispose to UEDVT whereas the risk of UEDVT declines with longer duration of MV.http://dx.doi.org/10.1155/2015/614598 |
| spellingShingle | Farah Al-Saffar Ena Gupta Furqan Siddiqi Muhammad Faisal Lisa M. Jones Vandana Seeram Mariam Louis James D. Cury Abubakr A. Bajwa Adil Shujaat Is There Any Association between PEEP and Upper Extremity DVT? Critical Care Research and Practice |
| title | Is There Any Association between PEEP and Upper Extremity DVT? |
| title_full | Is There Any Association between PEEP and Upper Extremity DVT? |
| title_fullStr | Is There Any Association between PEEP and Upper Extremity DVT? |
| title_full_unstemmed | Is There Any Association between PEEP and Upper Extremity DVT? |
| title_short | Is There Any Association between PEEP and Upper Extremity DVT? |
| title_sort | is there any association between peep and upper extremity dvt |
| url | http://dx.doi.org/10.1155/2015/614598 |
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