Spatial phenotyping of human bronchial airways in obstructive lung disease

Spatial phenotyping of human bronchial airways in obstructive lung disease

Abstract Chronic respiratory diseases such as asthma and COPD involve interactions between multiple resident and immune cell types within bronchial airways, resulting in structural and functional changes. Thus cellular heterogeneity, arrangements and associated neighborhoods as well as interactions...

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Bibliographic Details
Main Authors: Latifa Khalfaoui, Raymond M. Moore, Jose. C. Villasboas, Kaitlyn R. Whitaker, Brenna C. Novotny, Michael A. Thompson, Christina M. Pabelick, Y. S. Prakash
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Respiratory Research
Subjects:
Spatial biology
Functional phenotyping
CODEX
Asthma
COPD
Airway epithelium
Online Access:https://doi.org/10.1186/s12931-025-03315-5
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