Knockdown of Annexin A1 induces apoptosis, causing G2/M arrest and facilitating phagocytosis activity in human leukemia cell lines
Annexin A1 (ANXA1) is an endogenous protein involved in the control of proliferation, cell cycle, phagocytosis, and apoptosis in several types of cancer. To investigate the effects of ANXA1 knockdown in leukemia cells, transfection with specific ANXA1 siRNA was performed. Cell cycle and apoptosis we...
Saved in:
Main Authors: | Hasan Masyitah, Kumolosasi Endang, Jantan Ibrahim, Jasamai Malina, Nazarudin Norlaili |
---|---|
Format: | Article |
Language: | English |
Published: |
Sciendo
2022-03-01
|
Series: | Acta Pharmaceutica |
Subjects: | |
Online Access: | https://doi.org/10.2478/acph-2022-0005 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Effects of annexin A1 on apoptosis and cell cycle arrest in human leukemic cell lines
by: Sabran Affidah, et al.
Published: (2019-03-01) -
T14diLys/DOPE Liposomes: An Innovative Option for siRNA-Based Gene Knockdown?
by: Sophie Meinhard, et al.
Published: (2024-12-01) -
Ochratoxin A induces immunotoxicity by targeting Annexin A1 mediated neutrophil apoptosis in zebrafish
by: Yihong Zheng, et al.
Published: (2025-01-01) -
Phosphatidylserine on sperm head interact with Annexin A5 on oviduct luminal cilia to form a sperm reservoir in pigs
by: Lorraine Schmaltz, et al.
Published: (2025-03-01) -
The Protective Effects of Annexin A1 in Acute Lung Injury Mediated by Nrf2
by: Hui Huang, et al.
Published: (2025-01-01)