Comprehensive review of myocardial injury after noncardiac surgery: prevention, intervention, and long-term management strategies
Abstract Myocardial Injury after Noncardiac Surgery (MINS) is an increasingly recognized complication that significantly impacts postoperative morbidity and mortality. Characterized by elevated cardiac troponin levels without overt ischemic symptoms, MINS presents a challenge in perioperative care....
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| Format: | Article |
| Language: | English |
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BMC
2025-01-01
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| Series: | Journal of Cardiothoracic Surgery |
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| Online Access: | https://doi.org/10.1186/s13019-025-03358-1 |
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| author | Moiud Mohyeldin Sarah J. Norman Ayzia Carney Courtney Odza |
| author_facet | Moiud Mohyeldin Sarah J. Norman Ayzia Carney Courtney Odza |
| author_sort | Moiud Mohyeldin |
| collection | DOAJ |
| description | Abstract Myocardial Injury after Noncardiac Surgery (MINS) is an increasingly recognized complication that significantly impacts postoperative morbidity and mortality. Characterized by elevated cardiac troponin levels without overt ischemic symptoms, MINS presents a challenge in perioperative care. This review article explores the epidemiology, etiology, and management of MINS, with a particular focus on prevention and the latest management strategies. We discuss the role of aspirin, statins, anticoagulation, and Dual Antiplatelet Therapy (DAPT) within the context of MINS, drawing on evidence from notable clinical trials as well as observational studies. Despite advancements in understanding and managing MINS, the condition continues to be associated with high mortality and major adverse cardiovascular events (MACE), underscoring the need for ongoing research and development of more effective management protocols. |
| format | Article |
| id | doaj-art-5d509e2e0244474ebb4188d104e789b9 |
| institution | Kabale University |
| issn | 1749-8090 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Cardiothoracic Surgery |
| spelling | doaj-art-5d509e2e0244474ebb4188d104e789b92025-02-02T12:42:00ZengBMCJournal of Cardiothoracic Surgery1749-80902025-01-0120111010.1186/s13019-025-03358-1Comprehensive review of myocardial injury after noncardiac surgery: prevention, intervention, and long-term management strategiesMoiud Mohyeldin0Sarah J. Norman1Ayzia Carney2Courtney Odza3Faculty of Medicine, UMST UniversitySchool of Medicine, American University of the CaribbeanSchool of Medicine, American University of the CaribbeanSchool of Medicine, American University of the CaribbeanAbstract Myocardial Injury after Noncardiac Surgery (MINS) is an increasingly recognized complication that significantly impacts postoperative morbidity and mortality. Characterized by elevated cardiac troponin levels without overt ischemic symptoms, MINS presents a challenge in perioperative care. This review article explores the epidemiology, etiology, and management of MINS, with a particular focus on prevention and the latest management strategies. We discuss the role of aspirin, statins, anticoagulation, and Dual Antiplatelet Therapy (DAPT) within the context of MINS, drawing on evidence from notable clinical trials as well as observational studies. Despite advancements in understanding and managing MINS, the condition continues to be associated with high mortality and major adverse cardiovascular events (MACE), underscoring the need for ongoing research and development of more effective management protocols.https://doi.org/10.1186/s13019-025-03358-1Myocardial InjuryNoncardiac surgeryPreventionManagementCardiovascular Risk |
| spellingShingle | Moiud Mohyeldin Sarah J. Norman Ayzia Carney Courtney Odza Comprehensive review of myocardial injury after noncardiac surgery: prevention, intervention, and long-term management strategies Journal of Cardiothoracic Surgery Myocardial Injury Noncardiac surgery Prevention Management Cardiovascular Risk |
| title | Comprehensive review of myocardial injury after noncardiac surgery: prevention, intervention, and long-term management strategies |
| title_full | Comprehensive review of myocardial injury after noncardiac surgery: prevention, intervention, and long-term management strategies |
| title_fullStr | Comprehensive review of myocardial injury after noncardiac surgery: prevention, intervention, and long-term management strategies |
| title_full_unstemmed | Comprehensive review of myocardial injury after noncardiac surgery: prevention, intervention, and long-term management strategies |
| title_short | Comprehensive review of myocardial injury after noncardiac surgery: prevention, intervention, and long-term management strategies |
| title_sort | comprehensive review of myocardial injury after noncardiac surgery prevention intervention and long term management strategies |
| topic | Myocardial Injury Noncardiac surgery Prevention Management Cardiovascular Risk |
| url | https://doi.org/10.1186/s13019-025-03358-1 |
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