The association between daily movement behavior and adjusted handgrip strength in post-menopausal women

BackgroundThe factors driving the sarcopenia phenotype in post-menopausal women remain partly elusive. We thus investigated the associations of physical activity, sedentary behavior, and metabolic biomarkers with handgrip strength (HGS) as a marker of probable sarcopenia in Saudi post-menopausal wom...

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Main Authors: Aishah Alzuwaydi, Ghedeir M. Alshammari, Mohammed A. Mohammed, Rizwan Qaisar, M. Azhar Hussain, Shaea A. Alkahtani
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Nutrition
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Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2025.1538002/full
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author Aishah Alzuwaydi
Ghedeir M. Alshammari
Mohammed A. Mohammed
Rizwan Qaisar
M. Azhar Hussain
M. Azhar Hussain
Shaea A. Alkahtani
author_facet Aishah Alzuwaydi
Ghedeir M. Alshammari
Mohammed A. Mohammed
Rizwan Qaisar
M. Azhar Hussain
M. Azhar Hussain
Shaea A. Alkahtani
author_sort Aishah Alzuwaydi
collection DOAJ
description BackgroundThe factors driving the sarcopenia phenotype in post-menopausal women remain partly elusive. We thus investigated the associations of physical activity, sedentary behavior, and metabolic biomarkers with handgrip strength (HGS) as a marker of probable sarcopenia in Saudi post-menopausal women.MethodsWe recruited 268 post-menopausal women aged 50 years or above. Physical activity was assessed using Global Physical Activity Questionnaire (GPAQ), and body composition was measured with a BIA device. Blood samples were used to measure cholesterol and triglyceride levels. Blood pressure and waist circumference (WC) were measured. HGS was measured using a digital HGS dynamometer and an HGS < 16 kg was used to define probable sarcopenia. We applied the ordinary least squares (OLS) regression approach for the dependent variables HGS, HGS relative to skeletal muscle mass (SMM) and HGS relative to fat-to-mass ratio (FMR).ResultsPhysical activity was positively associated with HGS, and sedentary behavior was negatively associated with HGS (p < 0.05). HGS relative to body mass index (BMI) and SMM revealed significant negative relationships with WC (p < 0.05). Taking into account age and FMR, the association with HGS or HGS/SMM existed for physical activity (p < 0.05), sedentary behavior (p < 0.01), and WC (p < 0.001).ConclusionAltogether, we report that high physical activity, low sedentary behavior and low WC are negatively associated with a risk of low HGS among Saudi post-menopausal women.
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spelling doaj-art-5d3121e88f7e4eddbf9787dd54f98ad42025-08-20T03:41:00ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2025-03-011210.3389/fnut.2025.15380021538002The association between daily movement behavior and adjusted handgrip strength in post-menopausal womenAishah Alzuwaydi0Ghedeir M. Alshammari1Mohammed A. Mohammed2Rizwan Qaisar3M. Azhar Hussain4M. Azhar Hussain5Shaea A. Alkahtani6Department of Nutrition, College of Agriculture and Nutrition, King Saud University, Riyadh, Saudi ArabiaDepartment of Nutrition, College of Agriculture and Nutrition, King Saud University, Riyadh, Saudi ArabiaDepartment of Nutrition, College of Agriculture and Nutrition, King Saud University, Riyadh, Saudi ArabiaDepartment of Basic Medical Sciences, College of Medicine, University of Sharjah, Sharjah, United Arab EmiratesDepartment of Finance and Economics, College of Business Administration, University of Sharjah, Sharjah, United Arab EmiratesDepartment of Social Sciences and Business, Roskilde University, Roskilde, DenmarkDepartment of Exercise Physiology, College of Sport Sciences and Physical Activity, King Saud University, Riyadh, Saudi ArabiaBackgroundThe factors driving the sarcopenia phenotype in post-menopausal women remain partly elusive. We thus investigated the associations of physical activity, sedentary behavior, and metabolic biomarkers with handgrip strength (HGS) as a marker of probable sarcopenia in Saudi post-menopausal women.MethodsWe recruited 268 post-menopausal women aged 50 years or above. Physical activity was assessed using Global Physical Activity Questionnaire (GPAQ), and body composition was measured with a BIA device. Blood samples were used to measure cholesterol and triglyceride levels. Blood pressure and waist circumference (WC) were measured. HGS was measured using a digital HGS dynamometer and an HGS < 16 kg was used to define probable sarcopenia. We applied the ordinary least squares (OLS) regression approach for the dependent variables HGS, HGS relative to skeletal muscle mass (SMM) and HGS relative to fat-to-mass ratio (FMR).ResultsPhysical activity was positively associated with HGS, and sedentary behavior was negatively associated with HGS (p < 0.05). HGS relative to body mass index (BMI) and SMM revealed significant negative relationships with WC (p < 0.05). Taking into account age and FMR, the association with HGS or HGS/SMM existed for physical activity (p < 0.05), sedentary behavior (p < 0.01), and WC (p < 0.001).ConclusionAltogether, we report that high physical activity, low sedentary behavior and low WC are negatively associated with a risk of low HGS among Saudi post-menopausal women.https://www.frontiersin.org/articles/10.3389/fnut.2025.1538002/fullsarcopeniahandgrip strengthphysical activitysedentarypost-menopausal women
spellingShingle Aishah Alzuwaydi
Ghedeir M. Alshammari
Mohammed A. Mohammed
Rizwan Qaisar
M. Azhar Hussain
M. Azhar Hussain
Shaea A. Alkahtani
The association between daily movement behavior and adjusted handgrip strength in post-menopausal women
Frontiers in Nutrition
sarcopenia
handgrip strength
physical activity
sedentary
post-menopausal women
title The association between daily movement behavior and adjusted handgrip strength in post-menopausal women
title_full The association between daily movement behavior and adjusted handgrip strength in post-menopausal women
title_fullStr The association between daily movement behavior and adjusted handgrip strength in post-menopausal women
title_full_unstemmed The association between daily movement behavior and adjusted handgrip strength in post-menopausal women
title_short The association between daily movement behavior and adjusted handgrip strength in post-menopausal women
title_sort association between daily movement behavior and adjusted handgrip strength in post menopausal women
topic sarcopenia
handgrip strength
physical activity
sedentary
post-menopausal women
url https://www.frontiersin.org/articles/10.3389/fnut.2025.1538002/full
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