Type 2 Diabetes Mellitus and its Relationship with Obesity
Diabetes mellitus and visceral obesity are two closely related diseases, which are currently considered modern epidemics due to their high incidence, prevalence, complications and the economic expense they generate. An updated descriptive bibliographic review was carried out on diabetes mellitus and...
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| Format: | Article |
| Language: | Spanish |
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Universidad de las Ciencias Médicas de Cienfuegos
2025-01-01
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| Series: | Revista Finlay |
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| Online Access: | https://revfinlay.sld.cu/index.php/finlay/article/view/1428 |
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| author | Lina Neri Espinosa Pire Iruma Alfonso González Michelle Ariana Calvache Vargas Holger Alexander Lozano Ati |
| author_facet | Lina Neri Espinosa Pire Iruma Alfonso González Michelle Ariana Calvache Vargas Holger Alexander Lozano Ati |
| author_sort | Lina Neri Espinosa Pire |
| collection | DOAJ |
| description | Diabetes mellitus and visceral obesity are two closely related diseases, which are currently considered modern epidemics due to their high incidence, prevalence, complications and the economic expense they generate. An updated descriptive bibliographic review was carried out on diabetes mellitus and its relationship with obesity. Metasearch engines such as: Accessss, SUMSearch 2 and Epistemonikos were used and various databases such as: Pubmed, INASP, Cochrane, Karger, Embase, PsycINFO and LILACS. 18 bibliographic references were selected. The insulin resistance observed in diabetic patients with obesity is caused by inflammation and the presence of immune cells in adipose tissue. In the latter, substances such as leptin and resistin are secreted that increase insulin resistance. The decrease in sensitivity in the liver, skeletal muscle and fatty tissue produces hypoinsulinism and hyperglycemia through compensatory mechanisms. One of the main causes of type 2 diabetes mellitus is obesity, which generates a state of lipotoxicity in multiple organs, which initially decreases insulin sensitivity in the tissues and culminates in the deterioration of β-cell function. of the pancreas. |
| format | Article |
| id | doaj-art-5d30d648fbdb4f018d09f203f3499f65 |
| institution | Kabale University |
| issn | 2221-2434 |
| language | Spanish |
| publishDate | 2025-01-01 |
| publisher | Universidad de las Ciencias Médicas de Cienfuegos |
| record_format | Article |
| series | Revista Finlay |
| spelling | doaj-art-5d30d648fbdb4f018d09f203f3499f652025-01-30T21:22:03ZspaUniversidad de las Ciencias Médicas de CienfuegosRevista Finlay2221-24342025-01-01150e1428e1428749Type 2 Diabetes Mellitus and its Relationship with ObesityLina Neri Espinosa Pire0Iruma Alfonso González1Michelle Ariana Calvache Vargas2Holger Alexander Lozano Ati3Universidad Regional Autónoma de los Andes. Ambato. Tungurahua. Ecuador.Universidad Regional Autónoma de los Andes. Ambato. Tungurahua. Ecuador.Universidad Regional Autónoma de los Andes. Ambato. Tungurahua. Ecuador.Universidad Regional Autónoma de los Andes. Ambato. Tungurahua. Ecuador.Diabetes mellitus and visceral obesity are two closely related diseases, which are currently considered modern epidemics due to their high incidence, prevalence, complications and the economic expense they generate. An updated descriptive bibliographic review was carried out on diabetes mellitus and its relationship with obesity. Metasearch engines such as: Accessss, SUMSearch 2 and Epistemonikos were used and various databases such as: Pubmed, INASP, Cochrane, Karger, Embase, PsycINFO and LILACS. 18 bibliographic references were selected. The insulin resistance observed in diabetic patients with obesity is caused by inflammation and the presence of immune cells in adipose tissue. In the latter, substances such as leptin and resistin are secreted that increase insulin resistance. The decrease in sensitivity in the liver, skeletal muscle and fatty tissue produces hypoinsulinism and hyperglycemia through compensatory mechanisms. One of the main causes of type 2 diabetes mellitus is obesity, which generates a state of lipotoxicity in multiple organs, which initially decreases insulin sensitivity in the tissues and culminates in the deterioration of β-cell function. of the pancreas.https://revfinlay.sld.cu/index.php/finlay/article/view/1428diabetes mellitus tipo 2obesidad visceralinsulinorresistencia |
| spellingShingle | Lina Neri Espinosa Pire Iruma Alfonso González Michelle Ariana Calvache Vargas Holger Alexander Lozano Ati Type 2 Diabetes Mellitus and its Relationship with Obesity Revista Finlay diabetes mellitus tipo 2 obesidad visceral insulinorresistencia |
| title | Type 2 Diabetes Mellitus and its Relationship with Obesity |
| title_full | Type 2 Diabetes Mellitus and its Relationship with Obesity |
| title_fullStr | Type 2 Diabetes Mellitus and its Relationship with Obesity |
| title_full_unstemmed | Type 2 Diabetes Mellitus and its Relationship with Obesity |
| title_short | Type 2 Diabetes Mellitus and its Relationship with Obesity |
| title_sort | type 2 diabetes mellitus and its relationship with obesity |
| topic | diabetes mellitus tipo 2 obesidad visceral insulinorresistencia |
| url | https://revfinlay.sld.cu/index.php/finlay/article/view/1428 |
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