Flunarizine as a Candidate for Drug Repurposing Against Human Pathogenic Mammarenaviruses

Flunarizine as a Candidate for Drug Repurposing Against Human Pathogenic Mammarenaviruses

Lassa fever (LF), a viral hemorrhagic fever disease with a case fatality rate that can be over 20% among hospitalized LF patients, is endemic to many West African countries. Currently, no vaccines or therapies are specifically licensed to prevent or treat LF, hence the significance of developing the...

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Bibliographic Details
Main Authors: Chukwudi A. Ofodile, Ikemefuna C. Uzochukwu, Fortunatus C. Ezebuo, InnocentMary Ejiofor, Mercy Adebola, Innocent Okpoli, Beatrice Cubitt, Haydar Witwit, Chetachi B. Okwuanaso, Ngozi Onyemelukwe, Juan Carlos de la Torre
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Viruses
Subjects:
Lassa virus
LCMV
minigenome
in silico docking
flunarizine
antiviral
Online Access:https://www.mdpi.com/1999-4915/17/1/117
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