Human lung cancer neutrophils generate NETs with preserved anti-tumor cytotoxicity but impaired anti-migratory activity

Neutrophil extracellular traps (NETs) are DNA-protein structures released during a form of programmed neutrophil death known as NETosis. While NETs have been implicated in both tumor inhibition and promotion, their functional role in cancer remains ambiguous. In this study, we compared the NET-formi...

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Bibliographic Details
Main Authors: Nuha Alsharif, Mohamad Qaisi, Merav Shaul, Naomi Kaisar-Iluz, Dan Padawer, Osnath Bouhanna, Yael Volman, Zvi G. Fridlender
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1643609/full
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