Association of Habitual Physical Activity Measured by an Accelerometer with High-Density Lipoprotein Cholesterol Levels in Maintenance Hemodialysis Patients
After confirming the relationship between high-density lipoprotein cholesterol (HDL-C) levels and mortality in hemodialysis patients for study 1, we investigated the effect of physical activity on their HDL-C levels for study 2. In study 1, 266 hemodialysis patients were monitored prospectively for...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2013/780783 |
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| author | Ryota Matsuzawa Atsuhiko Matsunaga Toshiki Kutsuna Akira Ishii Yoshifumi Abe Kei Yoneki Manae Harada Mio Ishibashi Yasuo Takeuchi Atsushi Yoshida Naonobu Takahira |
| author_facet | Ryota Matsuzawa Atsuhiko Matsunaga Toshiki Kutsuna Akira Ishii Yoshifumi Abe Kei Yoneki Manae Harada Mio Ishibashi Yasuo Takeuchi Atsushi Yoshida Naonobu Takahira |
| author_sort | Ryota Matsuzawa |
| collection | DOAJ |
| description | After confirming the relationship between high-density lipoprotein cholesterol (HDL-C) levels and mortality in hemodialysis patients for study 1, we investigated the effect of physical activity on their HDL-C levels for study 2. In study 1, 266 hemodialysis patients were monitored prospectively for five years, and Cox proportional hazard regression confirmed the contribution of HDL-C to mortality. In study 2, 116 patients were recruited after excluding those with severe comorbidities or requiring assistance from another person to walk. Baseline characteristics, such as demographic factors, physical constitution, primary kidney disease, comorbid conditions, smoking habits, drug use, and laboratory parameters, were collected from patient hospital records. An accelerometer measured physical activity as the number of steps per day over five consecutive days, and multiple regression evaluated the association between physical activity and HDL-C levels. Seventy-seven patients died during the follow-up period. In study 1, we confirmed that HDL-C level was a significant predictor of mortality (P=0.03). After adjusting for patient characteristics in study 2, physical activity was independently associated with HDL-C levels (adjusted R2=0.255; P=0.005). In conclusion, physical inactivity was strongly associated with decreased HDL-C levels in hemodialysis patients. |
| format | Article |
| id | doaj-art-5cf32c7310984bb6a01eb52fb827fafd |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-5cf32c7310984bb6a01eb52fb827fafd2025-02-03T07:25:02ZengWileyThe Scientific World Journal1537-744X2013-01-01201310.1155/2013/780783780783Association of Habitual Physical Activity Measured by an Accelerometer with High-Density Lipoprotein Cholesterol Levels in Maintenance Hemodialysis PatientsRyota Matsuzawa0Atsuhiko Matsunaga1Toshiki Kutsuna2Akira Ishii3Yoshifumi Abe4Kei Yoneki5Manae Harada6Mio Ishibashi7Yasuo Takeuchi8Atsushi Yoshida9Naonobu Takahira10Department of Rehabilitation Sciences, Graduate School of Medical Sciences, Kitasato University, 1-15-1 Kitasato, Sagamihara, Kanagawa 252-0373, JapanDepartment of Rehabilitation Sciences, Graduate School of Medical Sciences, Kitasato University, 1-15-1 Kitasato, Sagamihara, Kanagawa 252-0373, JapanRehabilitation Center, Kitasato University East Hospital, Sagamihara, JapanHemodialysis Center, Sagami Junkanki Clinic, Sagamihara, JapanDepartment of Rehabilitation Sciences, Graduate School of Medical Sciences, Kitasato University, 1-15-1 Kitasato, Sagamihara, Kanagawa 252-0373, JapanDepartment of Rehabilitation Sciences, Graduate School of Medical Sciences, Kitasato University, 1-15-1 Kitasato, Sagamihara, Kanagawa 252-0373, JapanDepartment of Rehabilitation Sciences, Graduate School of Medical Sciences, Kitasato University, 1-15-1 Kitasato, Sagamihara, Kanagawa 252-0373, JapanHemodialysis Center, Sagami Junkanki Clinic, Sagamihara, JapanDivision of Nephrology, Department of Internal Medicine, Kitasato University School of Medicine, Sagamihara, JapanHemodialysis Center, Sagami Junkanki Clinic, Sagamihara, JapanDepartment of Rehabilitation Sciences, Graduate School of Medical Sciences, Kitasato University, 1-15-1 Kitasato, Sagamihara, Kanagawa 252-0373, JapanAfter confirming the relationship between high-density lipoprotein cholesterol (HDL-C) levels and mortality in hemodialysis patients for study 1, we investigated the effect of physical activity on their HDL-C levels for study 2. In study 1, 266 hemodialysis patients were monitored prospectively for five years, and Cox proportional hazard regression confirmed the contribution of HDL-C to mortality. In study 2, 116 patients were recruited after excluding those with severe comorbidities or requiring assistance from another person to walk. Baseline characteristics, such as demographic factors, physical constitution, primary kidney disease, comorbid conditions, smoking habits, drug use, and laboratory parameters, were collected from patient hospital records. An accelerometer measured physical activity as the number of steps per day over five consecutive days, and multiple regression evaluated the association between physical activity and HDL-C levels. Seventy-seven patients died during the follow-up period. In study 1, we confirmed that HDL-C level was a significant predictor of mortality (P=0.03). After adjusting for patient characteristics in study 2, physical activity was independently associated with HDL-C levels (adjusted R2=0.255; P=0.005). In conclusion, physical inactivity was strongly associated with decreased HDL-C levels in hemodialysis patients.http://dx.doi.org/10.1155/2013/780783 |
| spellingShingle | Ryota Matsuzawa Atsuhiko Matsunaga Toshiki Kutsuna Akira Ishii Yoshifumi Abe Kei Yoneki Manae Harada Mio Ishibashi Yasuo Takeuchi Atsushi Yoshida Naonobu Takahira Association of Habitual Physical Activity Measured by an Accelerometer with High-Density Lipoprotein Cholesterol Levels in Maintenance Hemodialysis Patients The Scientific World Journal |
| title | Association of Habitual Physical Activity Measured by an Accelerometer with High-Density Lipoprotein Cholesterol Levels in Maintenance Hemodialysis Patients |
| title_full | Association of Habitual Physical Activity Measured by an Accelerometer with High-Density Lipoprotein Cholesterol Levels in Maintenance Hemodialysis Patients |
| title_fullStr | Association of Habitual Physical Activity Measured by an Accelerometer with High-Density Lipoprotein Cholesterol Levels in Maintenance Hemodialysis Patients |
| title_full_unstemmed | Association of Habitual Physical Activity Measured by an Accelerometer with High-Density Lipoprotein Cholesterol Levels in Maintenance Hemodialysis Patients |
| title_short | Association of Habitual Physical Activity Measured by an Accelerometer with High-Density Lipoprotein Cholesterol Levels in Maintenance Hemodialysis Patients |
| title_sort | association of habitual physical activity measured by an accelerometer with high density lipoprotein cholesterol levels in maintenance hemodialysis patients |
| url | http://dx.doi.org/10.1155/2013/780783 |
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