Osteopathic Manipulative Treatment Limits Chronic Constipation in a Child with Pitt-Hopkins Syndrome
Pitt-Hopkins Syndrome (PTHS) is a rare genetic disorder caused by insufficient expression of the TCF4 gene. Children with PTHS typically present with gastrointestinal disorders and early severe chronic constipation is frequently found (75%). Here we describe the case of a PTHS male 10-year-old patie...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Case Reports in Pediatrics |
| Online Access: | http://dx.doi.org/10.1155/2017/5437830 |
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| author | Alessandro Aquino Mattia Perini Silvia Cosmai Silvia Zanon Viviana Pisa Carmine Castagna Stefano Uberti |
| author_facet | Alessandro Aquino Mattia Perini Silvia Cosmai Silvia Zanon Viviana Pisa Carmine Castagna Stefano Uberti |
| author_sort | Alessandro Aquino |
| collection | DOAJ |
| description | Pitt-Hopkins Syndrome (PTHS) is a rare genetic disorder caused by insufficient expression of the TCF4 gene. Children with PTHS typically present with gastrointestinal disorders and early severe chronic constipation is frequently found (75%). Here we describe the case of a PTHS male 10-year-old patient with chronic constipation in whom Osteopathic Manipulative Treatment (OMT) resulted in improved bowel functions, as assessed by the diary, the QPGS-Form A Section C questionnaire, and the Paediatric Bristol Stool Form Scale. The authors suggested that OMT may be a valid tool to improve the defecation frequency and reduce enema administration in PTHS patients. |
| format | Article |
| id | doaj-art-5ce53d0ddbe042b1a463821d3f9c4a30 |
| institution | Kabale University |
| issn | 2090-6803 2090-6811 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pediatrics |
| spelling | doaj-art-5ce53d0ddbe042b1a463821d3f9c4a302025-02-03T01:03:11ZengWileyCase Reports in Pediatrics2090-68032090-68112017-01-01201710.1155/2017/54378305437830Osteopathic Manipulative Treatment Limits Chronic Constipation in a Child with Pitt-Hopkins SyndromeAlessandro Aquino0Mattia Perini1Silvia Cosmai2Silvia Zanon3Viviana Pisa4Carmine Castagna5Stefano Uberti6Research Department, Istituto Superiore di Osteopatia, 20126 Milan, ItalyDepartment of Clinical Paediatrics & Obstetrics-Gynaecology, Istituto Superiore di Osteopatia, 20126 Milan, ItalyDepartment of Clinical Paediatrics & Obstetrics-Gynaecology, Istituto Superiore di Osteopatia, 20126 Milan, ItalyDepartment of Clinical Paediatrics & Obstetrics-Gynaecology, Istituto Superiore di Osteopatia, 20126 Milan, ItalyResearch Department, Istituto Superiore di Osteopatia, 20126 Milan, ItalyResearch Department, Istituto Superiore di Osteopatia, 20126 Milan, ItalyResearch Department, Istituto Superiore di Osteopatia, 20126 Milan, ItalyPitt-Hopkins Syndrome (PTHS) is a rare genetic disorder caused by insufficient expression of the TCF4 gene. Children with PTHS typically present with gastrointestinal disorders and early severe chronic constipation is frequently found (75%). Here we describe the case of a PTHS male 10-year-old patient with chronic constipation in whom Osteopathic Manipulative Treatment (OMT) resulted in improved bowel functions, as assessed by the diary, the QPGS-Form A Section C questionnaire, and the Paediatric Bristol Stool Form Scale. The authors suggested that OMT may be a valid tool to improve the defecation frequency and reduce enema administration in PTHS patients.http://dx.doi.org/10.1155/2017/5437830 |
| spellingShingle | Alessandro Aquino Mattia Perini Silvia Cosmai Silvia Zanon Viviana Pisa Carmine Castagna Stefano Uberti Osteopathic Manipulative Treatment Limits Chronic Constipation in a Child with Pitt-Hopkins Syndrome Case Reports in Pediatrics |
| title | Osteopathic Manipulative Treatment Limits Chronic Constipation in a Child with Pitt-Hopkins Syndrome |
| title_full | Osteopathic Manipulative Treatment Limits Chronic Constipation in a Child with Pitt-Hopkins Syndrome |
| title_fullStr | Osteopathic Manipulative Treatment Limits Chronic Constipation in a Child with Pitt-Hopkins Syndrome |
| title_full_unstemmed | Osteopathic Manipulative Treatment Limits Chronic Constipation in a Child with Pitt-Hopkins Syndrome |
| title_short | Osteopathic Manipulative Treatment Limits Chronic Constipation in a Child with Pitt-Hopkins Syndrome |
| title_sort | osteopathic manipulative treatment limits chronic constipation in a child with pitt hopkins syndrome |
| url | http://dx.doi.org/10.1155/2017/5437830 |
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