Pharmaceutical, Pharmacokinetic and Other Considerations for Intravenous to Oral Stepdown Therapy
Parenteral to oral stepdown therapy represents an effective cost containment strategy which can minimize intravenous therapy associated morbidity and may facilitate earlier hospital discharge. Several oral anti-infectives are available to the prescriber and there are as many opportunities to stepdow...
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Format: | Article |
Language: | English |
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Wiley
1995-01-01
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Series: | Canadian Journal of Infectious Diseases |
Online Access: | http://dx.doi.org/10.1155/1995/975209 |
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author | Peter J Jewesson |
author_facet | Peter J Jewesson |
author_sort | Peter J Jewesson |
collection | DOAJ |
description | Parenteral to oral stepdown therapy represents an effective cost containment strategy which can minimize intravenous therapy associated morbidity and may facilitate earlier hospital discharge. Several oral anti-infectives are available to the prescriber and there are as many opportunities to stepdown to the same agent as there are to other drugs of the same class or other classes. Recognition of the pharmacokinetic characteristics of these oral agents is essential lo successful therapy. Good bioavailability may not always be assured. A simple regimen will promote compliance. |
format | Article |
id | doaj-art-5ce1e48ed7ff4255904bbbb5a85a7ea7 |
institution | Kabale University |
issn | 1180-2332 |
language | English |
publishDate | 1995-01-01 |
publisher | Wiley |
record_format | Article |
series | Canadian Journal of Infectious Diseases |
spelling | doaj-art-5ce1e48ed7ff4255904bbbb5a85a7ea72025-02-03T01:11:18ZengWileyCanadian Journal of Infectious Diseases1180-23321995-01-016Suppl A11A16A10.1155/1995/975209Pharmaceutical, Pharmacokinetic and Other Considerations for Intravenous to Oral Stepdown TherapyPeter J Jewesson0Faculty of Pharmaceutical Sciences, University of British Columbia, Department of Pharmacy, Vancouver Hospital and Health Sciences Centre, Vancouver, British Columbia, CanadaParenteral to oral stepdown therapy represents an effective cost containment strategy which can minimize intravenous therapy associated morbidity and may facilitate earlier hospital discharge. Several oral anti-infectives are available to the prescriber and there are as many opportunities to stepdown to the same agent as there are to other drugs of the same class or other classes. Recognition of the pharmacokinetic characteristics of these oral agents is essential lo successful therapy. Good bioavailability may not always be assured. A simple regimen will promote compliance.http://dx.doi.org/10.1155/1995/975209 |
spellingShingle | Peter J Jewesson Pharmaceutical, Pharmacokinetic and Other Considerations for Intravenous to Oral Stepdown Therapy Canadian Journal of Infectious Diseases |
title | Pharmaceutical, Pharmacokinetic and Other Considerations for Intravenous to Oral Stepdown Therapy |
title_full | Pharmaceutical, Pharmacokinetic and Other Considerations for Intravenous to Oral Stepdown Therapy |
title_fullStr | Pharmaceutical, Pharmacokinetic and Other Considerations for Intravenous to Oral Stepdown Therapy |
title_full_unstemmed | Pharmaceutical, Pharmacokinetic and Other Considerations for Intravenous to Oral Stepdown Therapy |
title_short | Pharmaceutical, Pharmacokinetic and Other Considerations for Intravenous to Oral Stepdown Therapy |
title_sort | pharmaceutical pharmacokinetic and other considerations for intravenous to oral stepdown therapy |
url | http://dx.doi.org/10.1155/1995/975209 |
work_keys_str_mv | AT peterjjewesson pharmaceuticalpharmacokineticandotherconsiderationsforintravenoustooralstepdowntherapy |