Self-Assembled Peptide Hydrogels PPI45 and PPI47: Novel Drug Candidates for <i>Staphylococcus aureus</i> Infection Treatment

Self-Assembled Peptide Hydrogels PPI45 and PPI47: Novel Drug Candidates for <i>Staphylococcus aureus</i> Infection Treatment

<i>Staphylococcus aureus</i>, a prevalent zoonotic pathogen, poses a significant threat to skin wound infections. This study evaluates the bactericidal efficacy of self-assembled peptide hydrogels, PPI45 and PPI47, derived from the defensin-derived peptide PPI42, against <i>S. aure...

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Bibliographic Details
Main Authors: Quanlong Wu, Mengyin Deng, Ruoyu Mao, Na Yang, Ya Hao, Manli Cao, Da Teng, Jianhua Wang
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Gels
Subjects:
self-assembly gel
antimicrobial peptide
<i>Staphylococcus aureus</i>
mechanism
safety
Online Access:https://www.mdpi.com/2310-2861/11/1/63
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