Impact of Collagen on the Rheological and Transport Properties of Agarose Hydrogels

This work investigated how collagen addition affects the rheological and transport properties of agarose hydrogels. Collagen did not affect the rheological character of hydrogels (i.e., the overall shape of amplitude and frequency response curves) but changed their viscoelastic moduli and mesh size...

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Main Authors: Veronika Richterová, Alžběta Gjevik, Ondřej Vaculík, Jakub Vejrosta, Miloslav Pekař
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Gels
Subjects:
Online Access:https://www.mdpi.com/2310-2861/11/6/396
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author Veronika Richterová
Alžběta Gjevik
Ondřej Vaculík
Jakub Vejrosta
Miloslav Pekař
author_facet Veronika Richterová
Alžběta Gjevik
Ondřej Vaculík
Jakub Vejrosta
Miloslav Pekař
author_sort Veronika Richterová
collection DOAJ
description This work investigated how collagen addition affects the rheological and transport properties of agarose hydrogels. Collagen did not affect the rheological character of hydrogels (i.e., the overall shape of amplitude and frequency response curves) but changed their viscoelastic moduli and mesh size dependent on the concentration of both constituents. The diffusion coefficients of the oppositely charged model dyes eosin B and methylene blue were determined in all hydrogels and demonstrated a profound effect of electrostatic interactions. Comparison with similar work with fibroin addition showed that while the effects of these proteins on the viscoelastic properties of a polysaccharide network can be similar, their impact on network transport properties may be different.
format Article
id doaj-art-5ccc8a7cf5a64031bb84cebde8de06fb
institution Kabale University
issn 2310-2861
language English
publishDate 2025-05-01
publisher MDPI AG
record_format Article
series Gels
spelling doaj-art-5ccc8a7cf5a64031bb84cebde8de06fb2025-08-20T03:27:22ZengMDPI AGGels2310-28612025-05-0111639610.3390/gels11060396Impact of Collagen on the Rheological and Transport Properties of Agarose HydrogelsVeronika Richterová0Alžběta Gjevik1Ondřej Vaculík2Jakub Vejrosta3Miloslav Pekař4Institute of Physical and Applied Chemistry, Faculty of Chemistry, Brno University of Technology, 61200 Brno, Czech RepublicInstitute of Physical and Applied Chemistry, Faculty of Chemistry, Brno University of Technology, 61200 Brno, Czech RepublicInstitute of Scientific Instruments of the Czech Academy of Sciences, 61200 Brno, Czech RepublicInstitute of Scientific Instruments of the Czech Academy of Sciences, 61200 Brno, Czech RepublicInstitute of Physical and Applied Chemistry, Faculty of Chemistry, Brno University of Technology, 61200 Brno, Czech RepublicThis work investigated how collagen addition affects the rheological and transport properties of agarose hydrogels. Collagen did not affect the rheological character of hydrogels (i.e., the overall shape of amplitude and frequency response curves) but changed their viscoelastic moduli and mesh size dependent on the concentration of both constituents. The diffusion coefficients of the oppositely charged model dyes eosin B and methylene blue were determined in all hydrogels and demonstrated a profound effect of electrostatic interactions. Comparison with similar work with fibroin addition showed that while the effects of these proteins on the viscoelastic properties of a polysaccharide network can be similar, their impact on network transport properties may be different.https://www.mdpi.com/2310-2861/11/6/396agarosecollagenhydrogelsrheologymesh sizetransport
spellingShingle Veronika Richterová
Alžběta Gjevik
Ondřej Vaculík
Jakub Vejrosta
Miloslav Pekař
Impact of Collagen on the Rheological and Transport Properties of Agarose Hydrogels
Gels
agarose
collagen
hydrogels
rheology
mesh size
transport
title Impact of Collagen on the Rheological and Transport Properties of Agarose Hydrogels
title_full Impact of Collagen on the Rheological and Transport Properties of Agarose Hydrogels
title_fullStr Impact of Collagen on the Rheological and Transport Properties of Agarose Hydrogels
title_full_unstemmed Impact of Collagen on the Rheological and Transport Properties of Agarose Hydrogels
title_short Impact of Collagen on the Rheological and Transport Properties of Agarose Hydrogels
title_sort impact of collagen on the rheological and transport properties of agarose hydrogels
topic agarose
collagen
hydrogels
rheology
mesh size
transport
url https://www.mdpi.com/2310-2861/11/6/396
work_keys_str_mv AT veronikarichterova impactofcollagenontherheologicalandtransportpropertiesofagarosehydrogels
AT alzbetagjevik impactofcollagenontherheologicalandtransportpropertiesofagarosehydrogels
AT ondrejvaculik impactofcollagenontherheologicalandtransportpropertiesofagarosehydrogels
AT jakubvejrosta impactofcollagenontherheologicalandtransportpropertiesofagarosehydrogels
AT miloslavpekar impactofcollagenontherheologicalandtransportpropertiesofagarosehydrogels