Glomus Tumor of the Stomach: A Rare Cause of Upper Gastrointestinal Bleeding
Introduction. Glomus tumors (GTs) are benign neoplasm originating from the glomus body, commonly described in subungual region. The involvement abdominal is rare. Our aim is to describe a case of glomus tumor of the stomach that presented upper gastrointestinal bleeding. A 34-year-old woman was admi...
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Wiley
2011-01-01
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| Series: | Case Reports in Surgery |
| Online Access: | http://dx.doi.org/10.1155/2011/371082 |
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| author | Enzo Fabrício Ribeiro Nascimento Fábio Piovezan Fonte Roberta Laís Mendonça Ronaldo Nonose Carlos Alberto Fonte de Souza Carlos Augusto Real Martinez |
| author_facet | Enzo Fabrício Ribeiro Nascimento Fábio Piovezan Fonte Roberta Laís Mendonça Ronaldo Nonose Carlos Alberto Fonte de Souza Carlos Augusto Real Martinez |
| author_sort | Enzo Fabrício Ribeiro Nascimento |
| collection | DOAJ |
| description | Introduction. Glomus tumors (GTs) are benign neoplasm originating from the glomus body, commonly described in subungual region. The involvement abdominal is rare. Our aim is to describe a case of glomus tumor of the stomach that presented upper gastrointestinal bleeding. A 34-year-old woman was admitted with upper gastrointestinal bleeding and underwent an upper endoscopy that showed bleeding arising from an ulcerated lesion, treated by sclerosis therapy. A new endoscopy confirmed a submucosal lesion in upper portion of the stomach. During the laparotomy, a tumor at the upper anterior wall of gastric body was found and resected by a vertical gastrectomy. The pathological exam revealed hyperplastic smooth muscle fibers of the muscularis propria of the stomach wall, surrounded by hyaline stroma. The immunohistochemistry panel was positive for smooth muscle actin and type IV collagen, with low rate of mitosis studied by Ki-67 which allowed the final diagnosis of a gastric glomus tumor. Discussion. The majority of intraperitoneal glomus tumors occur in the stomach, and it is phenotypically similar to those localized in peripheral sites. Gastric GT generally is a benign tumor although it can be malignant and have the potential to metastasize. Conclusion. Even though gastric glomus tumor is rarely described, it should be considered as a possible cause of a major upper gastrointestinal bleeding. |
| format | Article |
| id | doaj-art-5cc11f97bef443e5a0a3f999cfb3f1e8 |
| institution | Kabale University |
| issn | 2090-6900 2090-6919 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
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| series | Case Reports in Surgery |
| spelling | doaj-art-5cc11f97bef443e5a0a3f999cfb3f1e82025-02-03T06:07:57ZengWileyCase Reports in Surgery2090-69002090-69192011-01-01201110.1155/2011/371082371082Glomus Tumor of the Stomach: A Rare Cause of Upper Gastrointestinal BleedingEnzo Fabrício Ribeiro Nascimento0Fábio Piovezan Fonte1Roberta Laís Mendonça2Ronaldo Nonose3Carlos Alberto Fonte de Souza4Carlos Augusto Real Martinez5Department of General Surgery, São Francisco University Hospital, 09190-370 Bragança Paulista, SP, BrazilSão Francisco University Medical School, 09190-370 Bragança Paulista, SP, BrazilSão Francisco University Medical School, 09190-370 Bragança Paulista, SP, BrazilDepartment of General Surgery, São Francisco University Hospital, 09190-370 Bragança Paulista, SP, BrazilDivision of Pathology, Specialized Center of Pathological Diagnosis (CEDAP), 09190-370 Bragança Paulista, SP, BrazilPost-Graduate Program in Health Sciences, São Francisco University, Rua Rui Barbosa, 255 Apto. 32, 09190-370 Santo André, SP, BrazilIntroduction. Glomus tumors (GTs) are benign neoplasm originating from the glomus body, commonly described in subungual region. The involvement abdominal is rare. Our aim is to describe a case of glomus tumor of the stomach that presented upper gastrointestinal bleeding. A 34-year-old woman was admitted with upper gastrointestinal bleeding and underwent an upper endoscopy that showed bleeding arising from an ulcerated lesion, treated by sclerosis therapy. A new endoscopy confirmed a submucosal lesion in upper portion of the stomach. During the laparotomy, a tumor at the upper anterior wall of gastric body was found and resected by a vertical gastrectomy. The pathological exam revealed hyperplastic smooth muscle fibers of the muscularis propria of the stomach wall, surrounded by hyaline stroma. The immunohistochemistry panel was positive for smooth muscle actin and type IV collagen, with low rate of mitosis studied by Ki-67 which allowed the final diagnosis of a gastric glomus tumor. Discussion. The majority of intraperitoneal glomus tumors occur in the stomach, and it is phenotypically similar to those localized in peripheral sites. Gastric GT generally is a benign tumor although it can be malignant and have the potential to metastasize. Conclusion. Even though gastric glomus tumor is rarely described, it should be considered as a possible cause of a major upper gastrointestinal bleeding.http://dx.doi.org/10.1155/2011/371082 |
| spellingShingle | Enzo Fabrício Ribeiro Nascimento Fábio Piovezan Fonte Roberta Laís Mendonça Ronaldo Nonose Carlos Alberto Fonte de Souza Carlos Augusto Real Martinez Glomus Tumor of the Stomach: A Rare Cause of Upper Gastrointestinal Bleeding Case Reports in Surgery |
| title | Glomus Tumor of the Stomach: A Rare Cause of Upper Gastrointestinal Bleeding |
| title_full | Glomus Tumor of the Stomach: A Rare Cause of Upper Gastrointestinal Bleeding |
| title_fullStr | Glomus Tumor of the Stomach: A Rare Cause of Upper Gastrointestinal Bleeding |
| title_full_unstemmed | Glomus Tumor of the Stomach: A Rare Cause of Upper Gastrointestinal Bleeding |
| title_short | Glomus Tumor of the Stomach: A Rare Cause of Upper Gastrointestinal Bleeding |
| title_sort | glomus tumor of the stomach a rare cause of upper gastrointestinal bleeding |
| url | http://dx.doi.org/10.1155/2011/371082 |
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