A Clinicopathological and Immunohistochemical Correlation in Cutaneous Metastases from Internal Malignancies: A Five-Year Study

Cutaneous metastases from internal malignancies are uncommon and occur in 0.6%–10.4% of all patients with cancer. In most cases, cutaneous metastases develop after the initial diagnosis of the primary internal malignancy and late in the course of the disease. Skin tumors are infrequent in Asian popu...

Full description

Saved in:
Bibliographic Details
Main Authors: Sarita Nibhoria, Kanwardeep Kaur Tiwana, Manmeet Kaur, Sumir Kumar
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Journal of Skin Cancer
Online Access:http://dx.doi.org/10.1155/2014/793937
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850226776811241472
author Sarita Nibhoria
Kanwardeep Kaur Tiwana
Manmeet Kaur
Sumir Kumar
author_facet Sarita Nibhoria
Kanwardeep Kaur Tiwana
Manmeet Kaur
Sumir Kumar
author_sort Sarita Nibhoria
collection DOAJ
description Cutaneous metastases from internal malignancies are uncommon and occur in 0.6%–10.4% of all patients with cancer. In most cases, cutaneous metastases develop after the initial diagnosis of the primary internal malignancy and late in the course of the disease. Skin tumors are infrequent in Asian population and cutaneous metastases are quite rare. Cutaneous metastases carry a poor prognosis with average survival of few months. In the present five-year study 1924 malignant tumors were screened which included only nine cases of cutaneous metastatic deposits. A wide range of site and clinical presentations including nodules, plaques, and ulcers was noted. Histopathological findings were significant and corresponded with the primary internal malignancy. Cutaneous metastases from breast carcinoma (44.4%) were the most common finding followed by non-Hodgkin lymphoma and renal cell carcinoma (22.2% each) and carcinoma cervix (11.1%). The aim of our study is to classify the cutaneous metastases and to evaluate their clinicopathologic and immunohistochemical correlation with the primary tumor.
format Article
id doaj-art-5cbfd39ccf9740aa8be7127516d10f6d
institution OA Journals
issn 2090-2905
2090-2913
language English
publishDate 2014-01-01
publisher Wiley
record_format Article
series Journal of Skin Cancer
spelling doaj-art-5cbfd39ccf9740aa8be7127516d10f6d2025-08-20T02:04:59ZengWileyJournal of Skin Cancer2090-29052090-29132014-01-01201410.1155/2014/793937793937A Clinicopathological and Immunohistochemical Correlation in Cutaneous Metastases from Internal Malignancies: A Five-Year StudySarita Nibhoria0Kanwardeep Kaur Tiwana1Manmeet Kaur2Sumir Kumar3Department of Pathology, G.G.S. Medical College & Hospital BFUHS, Faridkot, Punjab 151203, IndiaDepartment of Pathology, G.G.S. Medical College & Hospital BFUHS, Faridkot, Punjab 151203, IndiaDepartment of Pathology, G.G.S. Medical College & Hospital BFUHS, Faridkot, Punjab 151203, IndiaDepartment of Skin and VD, G.G.S. Medical College & Hospital BFUHS, Faridkot, Punjab 151203, IndiaCutaneous metastases from internal malignancies are uncommon and occur in 0.6%–10.4% of all patients with cancer. In most cases, cutaneous metastases develop after the initial diagnosis of the primary internal malignancy and late in the course of the disease. Skin tumors are infrequent in Asian population and cutaneous metastases are quite rare. Cutaneous metastases carry a poor prognosis with average survival of few months. In the present five-year study 1924 malignant tumors were screened which included only nine cases of cutaneous metastatic deposits. A wide range of site and clinical presentations including nodules, plaques, and ulcers was noted. Histopathological findings were significant and corresponded with the primary internal malignancy. Cutaneous metastases from breast carcinoma (44.4%) were the most common finding followed by non-Hodgkin lymphoma and renal cell carcinoma (22.2% each) and carcinoma cervix (11.1%). The aim of our study is to classify the cutaneous metastases and to evaluate their clinicopathologic and immunohistochemical correlation with the primary tumor.http://dx.doi.org/10.1155/2014/793937
spellingShingle Sarita Nibhoria
Kanwardeep Kaur Tiwana
Manmeet Kaur
Sumir Kumar
A Clinicopathological and Immunohistochemical Correlation in Cutaneous Metastases from Internal Malignancies: A Five-Year Study
Journal of Skin Cancer
title A Clinicopathological and Immunohistochemical Correlation in Cutaneous Metastases from Internal Malignancies: A Five-Year Study
title_full A Clinicopathological and Immunohistochemical Correlation in Cutaneous Metastases from Internal Malignancies: A Five-Year Study
title_fullStr A Clinicopathological and Immunohistochemical Correlation in Cutaneous Metastases from Internal Malignancies: A Five-Year Study
title_full_unstemmed A Clinicopathological and Immunohistochemical Correlation in Cutaneous Metastases from Internal Malignancies: A Five-Year Study
title_short A Clinicopathological and Immunohistochemical Correlation in Cutaneous Metastases from Internal Malignancies: A Five-Year Study
title_sort clinicopathological and immunohistochemical correlation in cutaneous metastases from internal malignancies a five year study
url http://dx.doi.org/10.1155/2014/793937
work_keys_str_mv AT saritanibhoria aclinicopathologicalandimmunohistochemicalcorrelationincutaneousmetastasesfrominternalmalignanciesafiveyearstudy
AT kanwardeepkaurtiwana aclinicopathologicalandimmunohistochemicalcorrelationincutaneousmetastasesfrominternalmalignanciesafiveyearstudy
AT manmeetkaur aclinicopathologicalandimmunohistochemicalcorrelationincutaneousmetastasesfrominternalmalignanciesafiveyearstudy
AT sumirkumar aclinicopathologicalandimmunohistochemicalcorrelationincutaneousmetastasesfrominternalmalignanciesafiveyearstudy
AT saritanibhoria clinicopathologicalandimmunohistochemicalcorrelationincutaneousmetastasesfrominternalmalignanciesafiveyearstudy
AT kanwardeepkaurtiwana clinicopathologicalandimmunohistochemicalcorrelationincutaneousmetastasesfrominternalmalignanciesafiveyearstudy
AT manmeetkaur clinicopathologicalandimmunohistochemicalcorrelationincutaneousmetastasesfrominternalmalignanciesafiveyearstudy
AT sumirkumar clinicopathologicalandimmunohistochemicalcorrelationincutaneousmetastasesfrominternalmalignanciesafiveyearstudy