Distinguishing classes of neuroactive drugs based on computational physicochemical properties and experimental phenotypic profiling in planarians.
Mental illnesses put a tremendous burden on afflicted individuals and society. Identification of novel drugs to treat such conditions is intrinsically challenging due to the complexity of neuropsychiatric diseases and the need for a systems-level understanding that goes beyond single molecule-target...
Saved in:
Main Authors: | Danielle Ireland, Christina Rabeler, Sagar Rao, Rudy J Richardson, Eva-Maria S Collins |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2025-01-01
|
Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0315394 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Biosynthesis of plant neuroactive alkaloids treating Alzheimer’s disease
by: Quanyu Yin, et al.
Published: (2025-02-01) -
Coordinated neuron-glia regeneration through Notch signaling in planarians.
by: M Lucila Scimone, et al.
Published: (2025-01-01) -
Stem cells (neoblasts) and positional information jointly dominate regeneration in planarians
by: Xuhui Chen
Published: (2025-01-01) -
Usp7 contributes to the tail regeneration of planarians via Islet/Wnt1 axis
by: Ang Liang, et al.
Published: (2025-01-01) -
Multi-omics unveils strain-specific neuroactive metabolite production linked to inflammation modulation by Bacteroides and their extracellular vesicles
by: Basit Yousuf, et al.
Published: (2025-01-01)