Primary Small-Cell Carcinoma of the Palate with Cushing’s Syndrome: A Case Report

We report a 24-year-old woman presenting with a relapsed soy-bean-size tender mass at the junction of the soft and hard palate and a history of palatine tumor of small cell carcinoma. Reexcision surgery was performed and histopathological features were consistent. The patient was treated with six cy...

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Main Authors: Yingqiu Song, Zhenyu Lin, Lingjuan Chen, Gang Wu
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Oncological Medicine
Online Access:http://dx.doi.org/10.1155/2012/539306
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author Yingqiu Song
Zhenyu Lin
Lingjuan Chen
Gang Wu
author_facet Yingqiu Song
Zhenyu Lin
Lingjuan Chen
Gang Wu
author_sort Yingqiu Song
collection DOAJ
description We report a 24-year-old woman presenting with a relapsed soy-bean-size tender mass at the junction of the soft and hard palate and a history of palatine tumor of small cell carcinoma. Reexcision surgery was performed and histopathological features were consistent. The patient was treated with six cycles of chemotherapy consisting of etoposide and cisplatin. After one year, the patient developed bone metastases and Cushing's syndrome, and successfully recovered with subsequent chemotherapy with irinotecan and cisplatin plus radiotherapy. There was no evidence of recurrence or metastasis for more than three years. Small cell carcinoma originating in the head and neck region has been reported to be highly aggressive and has a poor prognosis. This is the first case report of a patient with relapsed primary small cell carcinoma of the palate and successfully treated with second-line chemotherapy and local radiotherapy.
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publishDate 2012-01-01
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series Case Reports in Oncological Medicine
spelling doaj-art-5c7d674392b248d489e60c9bf93340002025-02-03T06:11:04ZengWileyCase Reports in Oncological Medicine2090-67062090-67142012-01-01201210.1155/2012/539306539306Primary Small-Cell Carcinoma of the Palate with Cushing’s Syndrome: A Case ReportYingqiu Song0Zhenyu Lin1Lingjuan Chen2Gang Wu3Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Hubei, ChinaCancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Hubei, ChinaCancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Hubei, ChinaCancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Hubei, ChinaWe report a 24-year-old woman presenting with a relapsed soy-bean-size tender mass at the junction of the soft and hard palate and a history of palatine tumor of small cell carcinoma. Reexcision surgery was performed and histopathological features were consistent. The patient was treated with six cycles of chemotherapy consisting of etoposide and cisplatin. After one year, the patient developed bone metastases and Cushing's syndrome, and successfully recovered with subsequent chemotherapy with irinotecan and cisplatin plus radiotherapy. There was no evidence of recurrence or metastasis for more than three years. Small cell carcinoma originating in the head and neck region has been reported to be highly aggressive and has a poor prognosis. This is the first case report of a patient with relapsed primary small cell carcinoma of the palate and successfully treated with second-line chemotherapy and local radiotherapy.http://dx.doi.org/10.1155/2012/539306
spellingShingle Yingqiu Song
Zhenyu Lin
Lingjuan Chen
Gang Wu
Primary Small-Cell Carcinoma of the Palate with Cushing’s Syndrome: A Case Report
Case Reports in Oncological Medicine
title Primary Small-Cell Carcinoma of the Palate with Cushing’s Syndrome: A Case Report
title_full Primary Small-Cell Carcinoma of the Palate with Cushing’s Syndrome: A Case Report
title_fullStr Primary Small-Cell Carcinoma of the Palate with Cushing’s Syndrome: A Case Report
title_full_unstemmed Primary Small-Cell Carcinoma of the Palate with Cushing’s Syndrome: A Case Report
title_short Primary Small-Cell Carcinoma of the Palate with Cushing’s Syndrome: A Case Report
title_sort primary small cell carcinoma of the palate with cushing s syndrome a case report
url http://dx.doi.org/10.1155/2012/539306
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AT lingjuanchen primarysmallcellcarcinomaofthepalatewithcushingssyndromeacasereport
AT gangwu primarysmallcellcarcinomaofthepalatewithcushingssyndromeacasereport