Robust Diffeomorphic Mapping via Geodesically Controlled Active Shapes

This paper presents recent advances in the use of diffeomorphic active shapes which incorporate the conservation laws of large deformation diffeomorphic metric mapping. The equations of evolution satisfying the conservation law are geodesics under the diffeomorphism metric and therefore termed geode...

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Main Authors: Daniel J. Tward, Jun Ma, Michael I. Miller, Laurent Younes
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:International Journal of Biomedical Imaging
Online Access:http://dx.doi.org/10.1155/2013/205494
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author Daniel J. Tward
Jun Ma
Michael I. Miller
Laurent Younes
author_facet Daniel J. Tward
Jun Ma
Michael I. Miller
Laurent Younes
author_sort Daniel J. Tward
collection DOAJ
description This paper presents recent advances in the use of diffeomorphic active shapes which incorporate the conservation laws of large deformation diffeomorphic metric mapping. The equations of evolution satisfying the conservation law are geodesics under the diffeomorphism metric and therefore termed geodesically controlled diffeomorphic active shapes (GDAS). Our principal application in this paper is on robust diffeomorphic mapping methods based on parameterized surface representations of subcortical template structures. Our parametrization of the GDAS evolution is via the initial momentum representation in the tangent space of the template surface. The dimension of this representation is constrained using principal component analysis generated from training samples. In this work, we seek to use template surfaces to generate segmentations of the hippocampus with three data attachment terms: surface matching, landmark matching, and inside-outside modeling from grayscale T1 MR imaging data. This is formulated as an energy minimization problem, where energy describes shape variability and data attachment accuracy, and we derive a variational solution. A gradient descent strategy is employed in the numerical optimization. For the landmark matching case, we demonstrate the robustness of this algorithm as applied to the workflow of a large neuroanatomical study by comparing to an existing diffeomorphic landmark matching algorithm.
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spelling doaj-art-5c762196517d416d89e2403c49831a5d2025-02-03T01:11:04ZengWileyInternational Journal of Biomedical Imaging1687-41881687-41962013-01-01201310.1155/2013/205494205494Robust Diffeomorphic Mapping via Geodesically Controlled Active ShapesDaniel J. Tward0Jun Ma1Michael I. Miller2Laurent Younes3Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21218, USADepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21218, USACenter for Imaging Science, Johns Hopkins University, Baltimore, MD 21218, USACenter for Imaging Science, Johns Hopkins University, Baltimore, MD 21218, USAThis paper presents recent advances in the use of diffeomorphic active shapes which incorporate the conservation laws of large deformation diffeomorphic metric mapping. The equations of evolution satisfying the conservation law are geodesics under the diffeomorphism metric and therefore termed geodesically controlled diffeomorphic active shapes (GDAS). Our principal application in this paper is on robust diffeomorphic mapping methods based on parameterized surface representations of subcortical template structures. Our parametrization of the GDAS evolution is via the initial momentum representation in the tangent space of the template surface. The dimension of this representation is constrained using principal component analysis generated from training samples. In this work, we seek to use template surfaces to generate segmentations of the hippocampus with three data attachment terms: surface matching, landmark matching, and inside-outside modeling from grayscale T1 MR imaging data. This is formulated as an energy minimization problem, where energy describes shape variability and data attachment accuracy, and we derive a variational solution. A gradient descent strategy is employed in the numerical optimization. For the landmark matching case, we demonstrate the robustness of this algorithm as applied to the workflow of a large neuroanatomical study by comparing to an existing diffeomorphic landmark matching algorithm.http://dx.doi.org/10.1155/2013/205494
spellingShingle Daniel J. Tward
Jun Ma
Michael I. Miller
Laurent Younes
Robust Diffeomorphic Mapping via Geodesically Controlled Active Shapes
International Journal of Biomedical Imaging
title Robust Diffeomorphic Mapping via Geodesically Controlled Active Shapes
title_full Robust Diffeomorphic Mapping via Geodesically Controlled Active Shapes
title_fullStr Robust Diffeomorphic Mapping via Geodesically Controlled Active Shapes
title_full_unstemmed Robust Diffeomorphic Mapping via Geodesically Controlled Active Shapes
title_short Robust Diffeomorphic Mapping via Geodesically Controlled Active Shapes
title_sort robust diffeomorphic mapping via geodesically controlled active shapes
url http://dx.doi.org/10.1155/2013/205494
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AT laurentyounes robustdiffeomorphicmappingviageodesicallycontrolledactiveshapes