Bilateral Basal Ganglion Hemorrhage after Severe Olanzapine Intoxication
Olanzapine is a second-generation antipsychotic drug which is generally considered safe with well therapeutic antipsychotic effects. We describe a patient suffering from bilateral intracerebral hemorrhage after severe olanzapine intoxication without underlying thrombocytopenia, arterial hypertension...
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Format: | Article |
Language: | English |
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Wiley
2020-01-01
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Series: | Case Reports in Psychiatry |
Online Access: | http://dx.doi.org/10.1155/2020/2398721 |
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author | Kerstin Schweyer Bastian Fatke Kornelia Kreiser Christian Rabe Christian Seifert Benno Ikenberg |
author_facet | Kerstin Schweyer Bastian Fatke Kornelia Kreiser Christian Rabe Christian Seifert Benno Ikenberg |
author_sort | Kerstin Schweyer |
collection | DOAJ |
description | Olanzapine is a second-generation antipsychotic drug which is generally considered safe with well therapeutic antipsychotic effects. We describe a patient suffering from bilateral intracerebral hemorrhage after severe olanzapine intoxication without underlying thrombocytopenia, arterial hypertension, or vascular malformation as cause of intracerebral hemorrhage. This raises the possibility of a direct side effect of high-dose olanzapine intake. So far, intracranial hemorrhage after olanzapine intoxication in such constellation has not been reported before. Given the high number of its prescription rates, our finding of intracranial hemorrhage after olanzapine intoxication is of high clinical relevance. |
format | Article |
id | doaj-art-5c33767fe47b46a485f60ec5f58226c9 |
institution | Kabale University |
issn | 2090-682X 2090-6838 |
language | English |
publishDate | 2020-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Psychiatry |
spelling | doaj-art-5c33767fe47b46a485f60ec5f58226c92025-02-03T01:04:48ZengWileyCase Reports in Psychiatry2090-682X2090-68382020-01-01202010.1155/2020/23987212398721Bilateral Basal Ganglion Hemorrhage after Severe Olanzapine IntoxicationKerstin Schweyer0Bastian Fatke1Kornelia Kreiser2Christian Rabe3Christian Seifert4Benno Ikenberg5Technical University of Munich, School of Medicine, Klinikum rechts der Isar, Department of Neurology, München, GermanyTechnical University of Munich, School of Medicine, Klinikum rechts der Isar, Department of Psychiatry and Psychotherapy, München, GermanyTechnical University of Munich, School of Medicine, Klinikum rechts der Isar, Department of Neuroradiology, München, GermanyTechnical University of Munich, School of Medicine, Department of Clinical Toxicology & Poison Control Centre Munich, Klinikum rechts der Isar, München, GermanyTechnical University of Munich, School of Medicine, Klinikum rechts der Isar, Department of Neurology, München, GermanyTechnical University of Munich, School of Medicine, Klinikum rechts der Isar, Department of Neurology, München, GermanyOlanzapine is a second-generation antipsychotic drug which is generally considered safe with well therapeutic antipsychotic effects. We describe a patient suffering from bilateral intracerebral hemorrhage after severe olanzapine intoxication without underlying thrombocytopenia, arterial hypertension, or vascular malformation as cause of intracerebral hemorrhage. This raises the possibility of a direct side effect of high-dose olanzapine intake. So far, intracranial hemorrhage after olanzapine intoxication in such constellation has not been reported before. Given the high number of its prescription rates, our finding of intracranial hemorrhage after olanzapine intoxication is of high clinical relevance.http://dx.doi.org/10.1155/2020/2398721 |
spellingShingle | Kerstin Schweyer Bastian Fatke Kornelia Kreiser Christian Rabe Christian Seifert Benno Ikenberg Bilateral Basal Ganglion Hemorrhage after Severe Olanzapine Intoxication Case Reports in Psychiatry |
title | Bilateral Basal Ganglion Hemorrhage after Severe Olanzapine Intoxication |
title_full | Bilateral Basal Ganglion Hemorrhage after Severe Olanzapine Intoxication |
title_fullStr | Bilateral Basal Ganglion Hemorrhage after Severe Olanzapine Intoxication |
title_full_unstemmed | Bilateral Basal Ganglion Hemorrhage after Severe Olanzapine Intoxication |
title_short | Bilateral Basal Ganglion Hemorrhage after Severe Olanzapine Intoxication |
title_sort | bilateral basal ganglion hemorrhage after severe olanzapine intoxication |
url | http://dx.doi.org/10.1155/2020/2398721 |
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