Multiple Abscess Collections: Antibiotics or Steroids?
Aseptic abscess syndrome (AAS) is a medical rarity. The combination of multiple abscess collections in different organs, negative microbiological studies, and the association with an inflammatory bowel disease is highly suggestive for an AAS. The AAS is an acute neutrophilic dermatosis, so “generali...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-01-01
|
| Series: | Case Reports in Immunology |
| Online Access: | http://dx.doi.org/10.1155/2024/3671685 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832548327731757056 |
|---|---|
| author | Philippe Raphael Dias Levin Bolt Christof Iking-Konert Mattia Arrigo Lars C. Huber |
| author_facet | Philippe Raphael Dias Levin Bolt Christof Iking-Konert Mattia Arrigo Lars C. Huber |
| author_sort | Philippe Raphael Dias |
| collection | DOAJ |
| description | Aseptic abscess syndrome (AAS) is a medical rarity. The combination of multiple abscess collections in different organs, negative microbiological studies, and the association with an inflammatory bowel disease is highly suggestive for an AAS. The AAS is an acute neutrophilic dermatosis, so “generalized pyoderma gangraenosum” or “generalized bullous sweet syndrome” might be used synonymously. It is important to note that the diagnosis of an AAS can be made only after careful exclusion of an infectious disease. Of interest, despite the severity of the inflammation, patients with AAS are commonly hemodynamically stable. To date, no studies have investigated the optimal regimen, dose, and duration of therapy. Corticosteroids are the cornerstone of immunosuppression during the acute phase. After the induction phase, therapy might be switched to anakinra or infliximab. |
| format | Article |
| id | doaj-art-5c27593dba804fc6af05b6705bd56905 |
| institution | Kabale University |
| issn | 2090-6617 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Immunology |
| spelling | doaj-art-5c27593dba804fc6af05b6705bd569052025-02-03T06:14:52ZengWileyCase Reports in Immunology2090-66172024-01-01202410.1155/2024/3671685Multiple Abscess Collections: Antibiotics or Steroids?Philippe Raphael Dias0Levin Bolt1Christof Iking-Konert2Mattia Arrigo3Lars C. Huber4Department of Internal MedicineDepartment of Internal MedicineDivision of RheumatologyDepartment of Internal MedicineDepartment of Internal MedicineAseptic abscess syndrome (AAS) is a medical rarity. The combination of multiple abscess collections in different organs, negative microbiological studies, and the association with an inflammatory bowel disease is highly suggestive for an AAS. The AAS is an acute neutrophilic dermatosis, so “generalized pyoderma gangraenosum” or “generalized bullous sweet syndrome” might be used synonymously. It is important to note that the diagnosis of an AAS can be made only after careful exclusion of an infectious disease. Of interest, despite the severity of the inflammation, patients with AAS are commonly hemodynamically stable. To date, no studies have investigated the optimal regimen, dose, and duration of therapy. Corticosteroids are the cornerstone of immunosuppression during the acute phase. After the induction phase, therapy might be switched to anakinra or infliximab.http://dx.doi.org/10.1155/2024/3671685 |
| spellingShingle | Philippe Raphael Dias Levin Bolt Christof Iking-Konert Mattia Arrigo Lars C. Huber Multiple Abscess Collections: Antibiotics or Steroids? Case Reports in Immunology |
| title | Multiple Abscess Collections: Antibiotics or Steroids? |
| title_full | Multiple Abscess Collections: Antibiotics or Steroids? |
| title_fullStr | Multiple Abscess Collections: Antibiotics or Steroids? |
| title_full_unstemmed | Multiple Abscess Collections: Antibiotics or Steroids? |
| title_short | Multiple Abscess Collections: Antibiotics or Steroids? |
| title_sort | multiple abscess collections antibiotics or steroids |
| url | http://dx.doi.org/10.1155/2024/3671685 |
| work_keys_str_mv | AT philipperaphaeldias multipleabscesscollectionsantibioticsorsteroids AT levinbolt multipleabscesscollectionsantibioticsorsteroids AT christofikingkonert multipleabscesscollectionsantibioticsorsteroids AT mattiaarrigo multipleabscesscollectionsantibioticsorsteroids AT larschuber multipleabscesscollectionsantibioticsorsteroids |