Relapsed Mantle Cell Lymphoma Presenting as “Sister Mary Joseph Nodule”
The finding of umbilical metastasis has historically been called a “Sister Mary Joseph Nodule”. A few case reports of lymphoma presenting in this manner have been documented. We report a case of relapsed mantle cell lymphoma (MCL) presenting as a Sister Mary Joseph's nodule. Although the few r...
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2010/708348 |
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| _version_ | 1832561218155446272 |
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| author | Jennifer E. Vaughn Ajay K. Gopal |
| author_facet | Jennifer E. Vaughn Ajay K. Gopal |
| author_sort | Jennifer E. Vaughn |
| collection | DOAJ |
| description | The finding of umbilical metastasis has historically been called a “Sister Mary Joseph Nodule”. A few case reports of lymphoma presenting in this manner have been documented. We report a case of relapsed mantle cell lymphoma (MCL) presenting as a Sister Mary Joseph's nodule. Although the few reports of lymphoma exhibiting umbilical metastasis suggest that patients may still expect a reasonable response to chemotherapy, this patient experienced multiple relapses, despite aggressive chemotherapy regimens. This clinical course is characteristic of the mantle cell form of non-hodgkin's lymphoma and illustrates a need to seek out more effective therapies. |
| format | Article |
| id | doaj-art-5c1def3bace54b208424abeaec1ffdfb |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-5c1def3bace54b208424abeaec1ffdfb2025-02-03T01:25:33ZengWileyCase Reports in Medicine1687-96271687-96352010-01-01201010.1155/2010/708348708348Relapsed Mantle Cell Lymphoma Presenting as “Sister Mary Joseph Nodule”Jennifer E. Vaughn0Ajay K. Gopal1Department of Internal Medicine, University of Washington, Box 39892. 325 Ninth Ave., Seattle, WA 98104, USADepartment of Internal Medicine, University of Washington, Box 39892. 325 Ninth Ave., Seattle, WA 98104, USAThe finding of umbilical metastasis has historically been called a “Sister Mary Joseph Nodule”. A few case reports of lymphoma presenting in this manner have been documented. We report a case of relapsed mantle cell lymphoma (MCL) presenting as a Sister Mary Joseph's nodule. Although the few reports of lymphoma exhibiting umbilical metastasis suggest that patients may still expect a reasonable response to chemotherapy, this patient experienced multiple relapses, despite aggressive chemotherapy regimens. This clinical course is characteristic of the mantle cell form of non-hodgkin's lymphoma and illustrates a need to seek out more effective therapies.http://dx.doi.org/10.1155/2010/708348 |
| spellingShingle | Jennifer E. Vaughn Ajay K. Gopal Relapsed Mantle Cell Lymphoma Presenting as “Sister Mary Joseph Nodule” Case Reports in Medicine |
| title | Relapsed Mantle Cell Lymphoma Presenting as “Sister Mary Joseph Nodule” |
| title_full | Relapsed Mantle Cell Lymphoma Presenting as “Sister Mary Joseph Nodule” |
| title_fullStr | Relapsed Mantle Cell Lymphoma Presenting as “Sister Mary Joseph Nodule” |
| title_full_unstemmed | Relapsed Mantle Cell Lymphoma Presenting as “Sister Mary Joseph Nodule” |
| title_short | Relapsed Mantle Cell Lymphoma Presenting as “Sister Mary Joseph Nodule” |
| title_sort | relapsed mantle cell lymphoma presenting as sister mary joseph nodule |
| url | http://dx.doi.org/10.1155/2010/708348 |
| work_keys_str_mv | AT jenniferevaughn relapsedmantlecelllymphomapresentingassistermaryjosephnodule AT ajaykgopal relapsedmantlecelllymphomapresentingassistermaryjosephnodule |