Intrapatient tacrolimus variability is associated with medical nonadherence among pediatric kidney transplant recipients
BackgroundLong-term survival of kidney allografts is limited by multiple factors, including nonadherence. High intrapatient variability in tacrolimus levels (≥30%) is associated with de novo donor-specific antibody (dnDSA) formation, increased risk of rejection and graft loss.MethodsWe prospectively...
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| Main Authors: | Tara B. Gavcovich, Vaka K. Sigurjonsdottir, Marissa J. DeFreitas, Claudia Serrano, Esther Rivas, Migdalia Jorge, Wacharee Seeherunvong, Chryso Katsoufis, Wendy Glaberson, Melisa Oliva, Adela D. Mattiazzi, Carolyn Abitbol, Jayanthi Chandar |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-03-01
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| Series: | Frontiers in Transplantation |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/frtra.2025.1572928/full |
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