Addition of Sildenafil in Patients with Pulmonary Arterial Hypertension with Inadequate Response to Bosentan Monotherapy
BACKGROUND: Pulmonary arterial hypertension (PAH) remains a progressive disease despite improvement when using one of three medication classes: prostanoids, endothelin receptor antagonists or phosphodiesterase-5 inhibitors. Combination therapy has been proposed for patients with unsatisfactory respo...
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| Format: | Article |
| Language: | English |
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Wiley
2008-01-01
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| Series: | Canadian Respiratory Journal |
| Online Access: | http://dx.doi.org/10.1155/2008/897102 |
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| _version_ | 1832555109946490880 |
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| author | Nancy R Porhownik Hassan Al-Sharif Zoheir Bshouty |
| author_facet | Nancy R Porhownik Hassan Al-Sharif Zoheir Bshouty |
| author_sort | Nancy R Porhownik |
| collection | DOAJ |
| description | BACKGROUND: Pulmonary arterial hypertension (PAH) remains a progressive disease despite improvement when using one of three medication classes: prostanoids, endothelin receptor antagonists or phosphodiesterase-5 inhibitors. Combination therapy has been proposed for patients with unsatisfactory response to monotherapy. |
| format | Article |
| id | doaj-art-5c0cb8f5b08c47ca9f6faa5bda7ab543 |
| institution | Kabale University |
| issn | 1198-2241 |
| language | English |
| publishDate | 2008-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Respiratory Journal |
| spelling | doaj-art-5c0cb8f5b08c47ca9f6faa5bda7ab5432025-02-03T05:49:33ZengWileyCanadian Respiratory Journal1198-22412008-01-0115842743010.1155/2008/897102Addition of Sildenafil in Patients with Pulmonary Arterial Hypertension with Inadequate Response to Bosentan MonotherapyNancy R Porhownik0Hassan Al-Sharif1Zoheir Bshouty2Department of Respiratory Medicine, University of Manitoba, Winnipeg, Manitoba, CanadaDepartment of Respiratory Medicine, University of Manitoba, Winnipeg, Manitoba, CanadaDepartment of Respiratory Medicine, University of Manitoba, Winnipeg, Manitoba, CanadaBACKGROUND: Pulmonary arterial hypertension (PAH) remains a progressive disease despite improvement when using one of three medication classes: prostanoids, endothelin receptor antagonists or phosphodiesterase-5 inhibitors. Combination therapy has been proposed for patients with unsatisfactory response to monotherapy.http://dx.doi.org/10.1155/2008/897102 |
| spellingShingle | Nancy R Porhownik Hassan Al-Sharif Zoheir Bshouty Addition of Sildenafil in Patients with Pulmonary Arterial Hypertension with Inadequate Response to Bosentan Monotherapy Canadian Respiratory Journal |
| title | Addition of Sildenafil in Patients with Pulmonary Arterial Hypertension with Inadequate Response to Bosentan Monotherapy |
| title_full | Addition of Sildenafil in Patients with Pulmonary Arterial Hypertension with Inadequate Response to Bosentan Monotherapy |
| title_fullStr | Addition of Sildenafil in Patients with Pulmonary Arterial Hypertension with Inadequate Response to Bosentan Monotherapy |
| title_full_unstemmed | Addition of Sildenafil in Patients with Pulmonary Arterial Hypertension with Inadequate Response to Bosentan Monotherapy |
| title_short | Addition of Sildenafil in Patients with Pulmonary Arterial Hypertension with Inadequate Response to Bosentan Monotherapy |
| title_sort | addition of sildenafil in patients with pulmonary arterial hypertension with inadequate response to bosentan monotherapy |
| url | http://dx.doi.org/10.1155/2008/897102 |
| work_keys_str_mv | AT nancyrporhownik additionofsildenafilinpatientswithpulmonaryarterialhypertensionwithinadequateresponsetobosentanmonotherapy AT hassanalsharif additionofsildenafilinpatientswithpulmonaryarterialhypertensionwithinadequateresponsetobosentanmonotherapy AT zoheirbshouty additionofsildenafilinpatientswithpulmonaryarterialhypertensionwithinadequateresponsetobosentanmonotherapy |