Subepithelial Corneal Deposits Associated with Exemestane

This is a case report of corneal deposits noted in a 69-year-old female patient taking the aromatase inhibitor, exemestane, after undergoing a mastectomy and chemotherapy for breast cancer. The patient presented to our eye clinic for a new-onset floater in one eye, and bilateral subepithelial opacit...

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Main Authors: Annahita Amireskandari, Elena Nguyen, David Hinkle, Thomas Mauger
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Ophthalmological Medicine
Online Access:http://dx.doi.org/10.1155/2020/5703164
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author Annahita Amireskandari
Elena Nguyen
David Hinkle
Thomas Mauger
author_facet Annahita Amireskandari
Elena Nguyen
David Hinkle
Thomas Mauger
author_sort Annahita Amireskandari
collection DOAJ
description This is a case report of corneal deposits noted in a 69-year-old female patient taking the aromatase inhibitor, exemestane, after undergoing a mastectomy and chemotherapy for breast cancer. The patient presented to our eye clinic for a new-onset floater in one eye, and bilateral subepithelial opacities were found incidentally on exam. The patient completed a 5-year course of the medication shortly after her initial visit with us and was noted to have a slight improvement in the density of the opacities on a follow-up visit 3 months later. We believe these corneal changes were most likely secondary to exemestane. The effect of aromatase inhibitors on the eye deserves further exploration as an increasing number of patients are prescribed these medications.
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series Case Reports in Ophthalmological Medicine
spelling doaj-art-5be2ada4961d465894c635927d9964142025-02-03T01:04:47ZengWileyCase Reports in Ophthalmological Medicine2090-67222090-67302020-01-01202010.1155/2020/57031645703164Subepithelial Corneal Deposits Associated with ExemestaneAnnahita Amireskandari0Elena Nguyen1David Hinkle2Thomas Mauger3Department of Ophthalmology, West Virginia University, USADepartment of Ophthalmology, West Virginia University, USADepartment of Ophthalmology, West Virginia University, USADepartment of Ophthalmology, West Virginia University, USAThis is a case report of corneal deposits noted in a 69-year-old female patient taking the aromatase inhibitor, exemestane, after undergoing a mastectomy and chemotherapy for breast cancer. The patient presented to our eye clinic for a new-onset floater in one eye, and bilateral subepithelial opacities were found incidentally on exam. The patient completed a 5-year course of the medication shortly after her initial visit with us and was noted to have a slight improvement in the density of the opacities on a follow-up visit 3 months later. We believe these corneal changes were most likely secondary to exemestane. The effect of aromatase inhibitors on the eye deserves further exploration as an increasing number of patients are prescribed these medications.http://dx.doi.org/10.1155/2020/5703164
spellingShingle Annahita Amireskandari
Elena Nguyen
David Hinkle
Thomas Mauger
Subepithelial Corneal Deposits Associated with Exemestane
Case Reports in Ophthalmological Medicine
title Subepithelial Corneal Deposits Associated with Exemestane
title_full Subepithelial Corneal Deposits Associated with Exemestane
title_fullStr Subepithelial Corneal Deposits Associated with Exemestane
title_full_unstemmed Subepithelial Corneal Deposits Associated with Exemestane
title_short Subepithelial Corneal Deposits Associated with Exemestane
title_sort subepithelial corneal deposits associated with exemestane
url http://dx.doi.org/10.1155/2020/5703164
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AT elenanguyen subepithelialcornealdepositsassociatedwithexemestane
AT davidhinkle subepithelialcornealdepositsassociatedwithexemestane
AT thomasmauger subepithelialcornealdepositsassociatedwithexemestane