Dual in vivo T cell depleted haploidentical hematopoietic stem cell transplantation with post-transplant cyclophosphamide and anti-thymocyte globulin as a third salvage transplant for leukocyte adhesion deficiency with graft failure: a case report

Dual in vivo T cell depleted haploidentical hematopoietic stem cell transplantation with post-transplant cyclophosphamide and anti-thymocyte globulin as a third salvage transplant for leukocyte adhesion deficiency with graft failure: a case report

BackgroundWith recent advances in clinical practice, including the use of reduced-toxicity conditioning regimens and innovative approaches such as ex vivo TCRαβ/CD19 depletion of haploidentical donor stem cells or post-transplant cyclophosphamide (PTCY), hematopoietic stem cell transplantation (HSCT...

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Bibliographic Details
Main Authors: Azadeh Kiumarsi, Amirarsalan Alaei, Mohsen Nikbakht, Saeed Mohammadi, Mohammad Reza Ostad-Ali, Zahra Rasti, Tahereh Rostami
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
inborn errors of immunity (IEI)
leukocyte adhesion deficiency (LAD)
hematopoietic stem cell transplantation (HSCT)
haploidentical
graft failure (GF)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1475448/full
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