Gabapentin-Induced Adrenal Insufficiency: The Hypothalamic-Pituitary-Adrenal Axis Stress Misresponse and Risk of Infection: A Case Report and Literature Review

Gabapentin-Induced Adrenal Insufficiency: The Hypothalamic-Pituitary-Adrenal Axis Stress Misresponse and Risk of Infection: A Case Report and Literature Review

This literature review, in light of the presented case report, explores the complex interplay between gabapentin (GBP), a gamma-aminobutyric acid (GABA) analog, and the hypothalamic–pituitary–adrenal (HPA) axis in patients undergoing major surgical procedures. It specifically investigates the potent...

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Bibliographic Details
Main Authors: Evmorfia Pechlivanidou, Alexandros Chatzikyriakos, Maria Anna Zisi, Nikolaos Paraskevopoulos, Semeli Kaltsa, Orestis K. Konstantas, Panteleimon Zogakis, Aikaterini Catsouli, Nick Sekouris, Rodanthi E. Margariti
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Pharmaceuticals
Subjects:
gabapentin
adrenal insufficiency
infections
HPA axis
stress responses
<i>Staphylococcus xylosus</i>
Online Access:https://www.mdpi.com/1424-8247/17/9/1174
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