Hyperexcitability in Spinal WDR Neurons following Experimental Disc Herniation Is Associated with Upregulation of Fractalkine and Its Receptor in Nucleus Pulposus and the Dorsal Root Ganglion

Introduction. Lumbar radicular pain following intervertebral disc herniation may be associated with a local inflammatory response induced by nucleus pulposus (NP) cells. Methods. In anaesthetized Lewis rats, extracellular single unit recordings of wide dynamic range (WDR) neurons in the dorsal horn...

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Bibliographic Details
Main Authors: Daniel Pitz Jacobsen, Aurora Moen, Fred Haugen, Johannes Gjerstad
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:International Journal of Inflammation
Online Access:http://dx.doi.org/10.1155/2016/6519408
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