Hyperexcitability in Spinal WDR Neurons following Experimental Disc Herniation Is Associated with Upregulation of Fractalkine and Its Receptor in Nucleus Pulposus and the Dorsal Root Ganglion
Introduction. Lumbar radicular pain following intervertebral disc herniation may be associated with a local inflammatory response induced by nucleus pulposus (NP) cells. Methods. In anaesthetized Lewis rats, extracellular single unit recordings of wide dynamic range (WDR) neurons in the dorsal horn...
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Main Authors: | Daniel Pitz Jacobsen, Aurora Moen, Fred Haugen, Johannes Gjerstad |
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Format: | Article |
Language: | English |
Published: |
Wiley
2016-01-01
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Series: | International Journal of Inflammation |
Online Access: | http://dx.doi.org/10.1155/2016/6519408 |
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