ZINQ-L: a zero-inflated quantile approach for differential abundance analysis of longitudinal microbiome data
BackgroundIdentifying bacterial taxa associated with disease phenotypes or clinical treatments over time is critical for understanding the underlying biological mechanism. Association testing for microbiome data is already challenging due to its complex distribution that involves sparsity, over-disp...
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Main Authors: | Shuai Li, Runzhe Li, John R. Lee, Ni Zhao, Wodan Ling |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2025-01-01
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Series: | Frontiers in Genetics |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fgene.2024.1494401/full |
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