Primary Small Cell Neuroendocrine Carcinoma of Paranasal Sinuses
Small cell neuroendocrine carcinoma of the paranasal sinuses is an extremely rare and aggressive neoplasm. Despite aggressive management, the tumor carries a poor prognosis, with a high risk of local recurrence or distant metastases. The management strategy is based on that for pulmonary small cell...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2014/874719 |
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| _version_ | 1832553397146877952 |
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| author | Maliha Khan Sobia Nizami Aibek E. Mirrakhimov Benjamin Maughan Justin A. Bishop William H. Sharfman |
| author_facet | Maliha Khan Sobia Nizami Aibek E. Mirrakhimov Benjamin Maughan Justin A. Bishop William H. Sharfman |
| author_sort | Maliha Khan |
| collection | DOAJ |
| description | Small cell neuroendocrine carcinoma of the paranasal sinuses is an extremely rare and aggressive neoplasm. Despite aggressive management, the tumor carries a poor prognosis, with a high risk of local recurrence or distant metastases. The management strategy is based on that for pulmonary small cell cancer and includes platinum-based chemotherapy combined with radiotherapy. We are reporting a case of an 89-year-old female patient diagnosed with small cell carcinoma of right-sided ethmoid and sphenoid sinuses. The tumor was found to have invaded the right orbit and anterior cranial fossa. Metastases to cervical lymph nodes and bone were also found. Due to the extended stage and poor prognosis of the patient, the management plan is palliative chemoradiotherapy. |
| format | Article |
| id | doaj-art-5b763f82dc704bcf8ea010a9cec09153 |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-5b763f82dc704bcf8ea010a9cec091532025-02-03T05:54:07ZengWileyCase Reports in Medicine1687-96271687-96352014-01-01201410.1155/2014/874719874719Primary Small Cell Neuroendocrine Carcinoma of Paranasal SinusesMaliha Khan0Sobia Nizami1Aibek E. Mirrakhimov2Benjamin Maughan3Justin A. Bishop4William H. Sharfman5Presence Saint Joseph Hospital, Department of Internal Medicine, 2900 N. Lake Shore Drive, Chicago, IL 60657, USADepartment of Medicine, Aga Khan University, Karachi, Sindh 74800, PakistanPresence Saint Joseph Hospital, Department of Internal Medicine, 2900 N. Lake Shore Drive, Chicago, IL 60657, USASidney Kimmel Comprehensive Cancer Center, John Hopkins University, Baltimore, MD 21287, USASidney Kimmel Comprehensive Cancer Center, John Hopkins University, Baltimore, MD 21287, USASidney Kimmel Comprehensive Cancer Center, John Hopkins University, Baltimore, MD 21287, USASmall cell neuroendocrine carcinoma of the paranasal sinuses is an extremely rare and aggressive neoplasm. Despite aggressive management, the tumor carries a poor prognosis, with a high risk of local recurrence or distant metastases. The management strategy is based on that for pulmonary small cell cancer and includes platinum-based chemotherapy combined with radiotherapy. We are reporting a case of an 89-year-old female patient diagnosed with small cell carcinoma of right-sided ethmoid and sphenoid sinuses. The tumor was found to have invaded the right orbit and anterior cranial fossa. Metastases to cervical lymph nodes and bone were also found. Due to the extended stage and poor prognosis of the patient, the management plan is palliative chemoradiotherapy.http://dx.doi.org/10.1155/2014/874719 |
| spellingShingle | Maliha Khan Sobia Nizami Aibek E. Mirrakhimov Benjamin Maughan Justin A. Bishop William H. Sharfman Primary Small Cell Neuroendocrine Carcinoma of Paranasal Sinuses Case Reports in Medicine |
| title | Primary Small Cell Neuroendocrine Carcinoma of Paranasal Sinuses |
| title_full | Primary Small Cell Neuroendocrine Carcinoma of Paranasal Sinuses |
| title_fullStr | Primary Small Cell Neuroendocrine Carcinoma of Paranasal Sinuses |
| title_full_unstemmed | Primary Small Cell Neuroendocrine Carcinoma of Paranasal Sinuses |
| title_short | Primary Small Cell Neuroendocrine Carcinoma of Paranasal Sinuses |
| title_sort | primary small cell neuroendocrine carcinoma of paranasal sinuses |
| url | http://dx.doi.org/10.1155/2014/874719 |
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