Deciphering human endogenous retrovirus expression in colorectal cancers: exploratory analysis regarding prognostic value in liver metastasesResearch in context

Deciphering human endogenous retrovirus expression in colorectal cancers: exploratory analysis regarding prognostic value in liver metastasesResearch in context

Summary: Background: Human Endogenous RetroVirus (HERV) expression in tumours reflects epigenetic dysregulation of cancer and an oncogenic factor through promoter/enhancer action on genes. While more than 50% of colorectal cancers develop liver metastases, HERV has not been studied in this context....

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Main Authors: Julien Viot, Romain Loyon, Nawfel Adib, Pierre Laurent-Puig, Aurélien de Reyniès, Fabrice André, Franck Monnien, Thierry André, Magali Svrcek, Anthony Turpin, Zohair Selmani, Laurent Arnould, Laura Guyard, Nicolas Gilbert, Anthony Boureux, Olivier Adotevi, Angélique Vienot, Syrine Abdeljaoued, Dewi Vernerey, Christophe Borg, Daniel Gautheret
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:EBioMedicine
Subjects:
Transposable elements
Endogenous retrovirus
Colorectal cancer
Liver metastases
Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396425001719
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