Validation of Indonesian Graves’ Ophthalmopathy Quality of Life Questionnaire and Its Association with Clinical Activity and Severity of Graves’ Ophthalmopathy
Background: Graves’ ophthalmopathy (GO) ocular abnormalities can persist even after treatment, negatively impacting patients’ psychological and social health. The Indonesian Graves’ Ophthalmopathy Quality of Life (GO-QoL) Questionnaire has not been validated, hence it cannot measure patient quality...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Interna Publishing
2024-10-01
|
| Series: | Acta Medica Indonesiana |
| Subjects: | |
| Online Access: | https://actamedindones.org/index.php/ijim/article/view/2647 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832585128223703040 |
|---|---|
| author | Cecilia Anggraini Syntia Nusanti Dicky Levenus Tahapary Levina Chandra Khoe |
| author_facet | Cecilia Anggraini Syntia Nusanti Dicky Levenus Tahapary Levina Chandra Khoe |
| author_sort | Cecilia Anggraini |
| collection | DOAJ |
| description | Background: Graves’ ophthalmopathy (GO) ocular abnormalities can persist even after treatment, negatively impacting patients’ psychological and social health. The Indonesian Graves’ Ophthalmopathy Quality of Life (GO-QoL) Questionnaire has not been validated, hence it cannot measure patient quality of life, which is crucial to GO treatment. We aimed to provide a reliable Indonesian GO-QoL Questionnaire and identify an association between patient quality of life and clinical activity and the severity of GO. Methods: The process of questionnaire validation involves transcultural adaptation and a cross-sectional design. The content validity index (CVI) and Cronbach’s alpha assessed validity and reliability, respectively. Results: The CVI was 1.00 for the Indonesian GO-QoL questionnaire. The Cronbach’s alpha for the visual function subscale value was 0.971, the appearance subscale value was 0.993, and the total score was 0.986. The appearance subscale and total score of GO patients’ quality of life had a significant association with clinical activity score (p<0.05) and disease severity (p<0.001). Conclusion: The Indonesian version of the GO-QoL has good validity and reliability. Both the active clinical activity of GO and the severity of the disease decreased patients’ appearance and general quality of life. |
| format | Article |
| id | doaj-art-5b5a95b10f3944c485188977cd9ac1a8 |
| institution | Kabale University |
| issn | 0125-9326 2338-2732 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | Interna Publishing |
| record_format | Article |
| series | Acta Medica Indonesiana |
| spelling | doaj-art-5b5a95b10f3944c485188977cd9ac1a82025-01-27T04:12:06ZengInterna PublishingActa Medica Indonesiana0125-93262338-27322024-10-01564693Validation of Indonesian Graves’ Ophthalmopathy Quality of Life Questionnaire and Its Association with Clinical Activity and Severity of Graves’ OphthalmopathyCecilia Anggraini0Syntia Nusanti1Dicky Levenus Tahapary2Levina Chandra Khoe3Residency Program in Ophthalmology, Faculty of Medicine Universitas Indonesia - Dr. Cipto Mangunkusumo Hospital, Jakarta, IndonesiaNeuro-ophthalmology Division, Department of Ophthalmology, Faculty of Medicine Universitas Indonesia - Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia.Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Dr. Cipto Mangunkusumo Hospital, Jakarta, IndonesiaDepartment of Community Medicine, Faculty of Medicine Universitas Indonesia, Jakarta, IndonesiaBackground: Graves’ ophthalmopathy (GO) ocular abnormalities can persist even after treatment, negatively impacting patients’ psychological and social health. The Indonesian Graves’ Ophthalmopathy Quality of Life (GO-QoL) Questionnaire has not been validated, hence it cannot measure patient quality of life, which is crucial to GO treatment. We aimed to provide a reliable Indonesian GO-QoL Questionnaire and identify an association between patient quality of life and clinical activity and the severity of GO. Methods: The process of questionnaire validation involves transcultural adaptation and a cross-sectional design. The content validity index (CVI) and Cronbach’s alpha assessed validity and reliability, respectively. Results: The CVI was 1.00 for the Indonesian GO-QoL questionnaire. The Cronbach’s alpha for the visual function subscale value was 0.971, the appearance subscale value was 0.993, and the total score was 0.986. The appearance subscale and total score of GO patients’ quality of life had a significant association with clinical activity score (p<0.05) and disease severity (p<0.001). Conclusion: The Indonesian version of the GO-QoL has good validity and reliability. Both the active clinical activity of GO and the severity of the disease decreased patients’ appearance and general quality of life.https://actamedindones.org/index.php/ijim/article/view/2647graves ophthalmopathyquality of lifequestionnaireindonesian go-qol |
| spellingShingle | Cecilia Anggraini Syntia Nusanti Dicky Levenus Tahapary Levina Chandra Khoe Validation of Indonesian Graves’ Ophthalmopathy Quality of Life Questionnaire and Its Association with Clinical Activity and Severity of Graves’ Ophthalmopathy Acta Medica Indonesiana graves ophthalmopathy quality of life questionnaire indonesian go-qol |
| title | Validation of Indonesian Graves’ Ophthalmopathy Quality of Life Questionnaire and Its Association with Clinical Activity and Severity of Graves’ Ophthalmopathy |
| title_full | Validation of Indonesian Graves’ Ophthalmopathy Quality of Life Questionnaire and Its Association with Clinical Activity and Severity of Graves’ Ophthalmopathy |
| title_fullStr | Validation of Indonesian Graves’ Ophthalmopathy Quality of Life Questionnaire and Its Association with Clinical Activity and Severity of Graves’ Ophthalmopathy |
| title_full_unstemmed | Validation of Indonesian Graves’ Ophthalmopathy Quality of Life Questionnaire and Its Association with Clinical Activity and Severity of Graves’ Ophthalmopathy |
| title_short | Validation of Indonesian Graves’ Ophthalmopathy Quality of Life Questionnaire and Its Association with Clinical Activity and Severity of Graves’ Ophthalmopathy |
| title_sort | validation of indonesian graves ophthalmopathy quality of life questionnaire and its association with clinical activity and severity of graves ophthalmopathy |
| topic | graves ophthalmopathy quality of life questionnaire indonesian go-qol |
| url | https://actamedindones.org/index.php/ijim/article/view/2647 |
| work_keys_str_mv | AT ceciliaanggraini validationofindonesiangravesophthalmopathyqualityoflifequestionnaireanditsassociationwithclinicalactivityandseverityofgravesophthalmopathy AT syntianusanti validationofindonesiangravesophthalmopathyqualityoflifequestionnaireanditsassociationwithclinicalactivityandseverityofgravesophthalmopathy AT dickylevenustahapary validationofindonesiangravesophthalmopathyqualityoflifequestionnaireanditsassociationwithclinicalactivityandseverityofgravesophthalmopathy AT levinachandrakhoe validationofindonesiangravesophthalmopathyqualityoflifequestionnaireanditsassociationwithclinicalactivityandseverityofgravesophthalmopathy |