Pathophysiological role of endothelial biomarkers in Bothrops sp. venom-induced renal dysfunction and the therapeutic effect of antivenom

Pathophysiological role of endothelial biomarkers in Bothrops sp. venom-induced renal dysfunction and the therapeutic effect of antivenom

Snakebite antivenom (SAV) is the standard treatment option to neutralize the toxic effects of snake venom, but their consequences on kidney function need to be better understood. This study aims to evaluate the effects of antivenom on kidney and endothelial biomarkers due to Bothrops venom in two su...

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Main Authors: Nicole Coelho Lopes, Gdayllon Cavalcante Meneses, Ranieri Sales de Souza Santos, Leticia Machado de Araújo, Bruna Viana Barroso Martins, Katarina Maria dos Reis Araújo, Valéria Holanda Nogueira de Aquino, Igor Moreira de Almeida, Sandra Mara Brasileiro Mota, Geraldo Bezerra da Silva Junior, Camila Eleuterio Rodrigues, Elizabeth De Francesco Daher, Polianna Lemos Moura Moreira Albuquerque, Alice Maria Costa Martins
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Toxicon: X
Subjects:
Snakebite
Antivenom
Kidney injury
Vascular cell adhesion molecule-1
Angiopoietins
KIM-1
Online Access:http://www.sciencedirect.com/science/article/pii/S259017102500013X
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