Phenolic Composition, and Antioxidant and Antineurodegenerative Potential of Methanolic Extracts of Fruit Peel and Flesh of Pear Varieties from Serbia
Pear ( Pyrus communis L.) is consumed as fresh fruit, in numerous food products, and also used as a traditional remedy in various countries, including Serbia. In search of bioactive compounds, six traditional pear varieties (‘Vidovača’, ‘Lubeničarka’, ‘Karamanka’, ‘Jeribasma’, ‘Lončara’, ‘Takiša’)...
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Institute of Animal Reproduction and Food Research of the Polish Academy of Sciences
2021-06-01
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| Series: | Polish Journal of Food and Nutrition Sciences |
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| Online Access: | http://journal.pan.olsztyn.pl/Phenolic-Composition-and-Antioxidant-and-Antineurodegenerative-Potential-of-Methanolic,138320,0,2.html |
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| author | Aleksandra Savić Ana Alimpić Aradski Jelena Živković Katarina Šavikin Snežana Jarić Petar D. Marin Sonja Duletić-Laušević |
| author_facet | Aleksandra Savić Ana Alimpić Aradski Jelena Živković Katarina Šavikin Snežana Jarić Petar D. Marin Sonja Duletić-Laušević |
| author_sort | Aleksandra Savić |
| collection | DOAJ |
| description | Pear ( Pyrus communis L.) is consumed as fresh fruit, in numerous food products, and also used as a traditional remedy in various countries, including Serbia. In search of bioactive compounds, six traditional pear varieties (‘Vidovača’, ‘Lubeničarka’, ‘Karamanka’, ‘Jeribasma’, ‘Lončara’, ‘Takiša’) and wild pear from Serbia were investigated and compared with a commercial variety (‘Williams Bartlett’). The aim of this study was to determine the total phenolic and flavonoid contents, phenolic composition, antioxidant capacity, and antineurodegenerative activities of methanolic extracts of peel, flesh, and mixed peel and flesh of pear fruits. Phenolic composition of extracts was determined with HPLC-DAD, while the antioxidant activity of extracts was evaluated by 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS), and ferric-reducing antioxidant power (FRAP) assays. Bearing in mind that oxidative stress is closely linked to neurodegeneration, the antineurodegenerative potential of the extracts was assessed by the inhibition of acetycholineserase (AChE) and tyrosinase (TYR) activities. The extracts of traditional varieties, particularly peel extracts, had a high content of phenolics, as well as significant antioxidant and moderate antineurodegenerative potential, compared to the commercial variety. The highest contents of total flavonoids and individual compounds, such as arbutin and chlorogenic acid, as well as the strongest antioxidant and TYR inhibitory activities were reported for the ‘Takiša’ peel extract. The performed analyses have revealed that fruits of traditional Serbian pear varieties are rich in bioactive components and could be used as functional food and for possible nutraceutical applications, to prevent diseases induced by oxidative stress. |
| format | Article |
| id | doaj-art-5b4482a4cfd14613bc31269d0ea4efca |
| institution | Kabale University |
| issn | 2083-6007 |
| language | English |
| publishDate | 2021-06-01 |
| publisher | Institute of Animal Reproduction and Food Research of the Polish Academy of Sciences |
| record_format | Article |
| series | Polish Journal of Food and Nutrition Sciences |
| spelling | doaj-art-5b4482a4cfd14613bc31269d0ea4efca2025-02-02T00:03:37ZengInstitute of Animal Reproduction and Food Research of the Polish Academy of SciencesPolish Journal of Food and Nutrition Sciences2083-60072021-06-0171222523610.31883/pjfns/138320138320Phenolic Composition, and Antioxidant and Antineurodegenerative Potential of Methanolic Extracts of Fruit Peel and Flesh of Pear Varieties from SerbiaAleksandra Savić0Ana Alimpić Aradski1Jelena Živković2Katarina Šavikin3Snežana Jarić4Petar D. Marin5Sonja Duletić-Laušević6Department for Education and Communication, Natural History Museum in Belgrade, Njegoševa 51, 11000 Belgrade, SerbiaInstitute of Botany and Botanical Garden "Jevremovac", Takovska 43, 11000 Belgrade, Serbia, University of Belgrade - Faculty of Biology, SerbiaInstitute for Medicinal Plant Research “Dr. Josif Pančić”, Institute for Medicinal Plant Research “Dr. Josif Pančić”, Tadeuša Košćuška 1, 11000 Belgrade, SerbiaInstitute for Medicinal Plant Research “Dr. Josif Pančić”, Institute for Medicinal Plant Research “Dr. Josif Pančić”, Tadeuša Košćuška 1, 11000 Belgrade, SerbiaDepartment of Ecology, University of Belgrade, Institute for Biological Research ‘Siniša Stanković’, Bulevar Despota Stefana 142, Belgrade, SerbiaDepartment of experimental and applied botany, University of Belgrade - Faculty of Biology, Institute of Botany and Botanical Garden "Jevremovac", Takovska 43, 11000 Belgrade, SerbiaDepartment of experimental and applied botany, University of Belgrade - Faculty of Biology, Institute of Botany and Botanical Garden "Jevremovac", Takovska 43, 11000 Belgrade, SerbiaPear ( Pyrus communis L.) is consumed as fresh fruit, in numerous food products, and also used as a traditional remedy in various countries, including Serbia. In search of bioactive compounds, six traditional pear varieties (‘Vidovača’, ‘Lubeničarka’, ‘Karamanka’, ‘Jeribasma’, ‘Lončara’, ‘Takiša’) and wild pear from Serbia were investigated and compared with a commercial variety (‘Williams Bartlett’). The aim of this study was to determine the total phenolic and flavonoid contents, phenolic composition, antioxidant capacity, and antineurodegenerative activities of methanolic extracts of peel, flesh, and mixed peel and flesh of pear fruits. Phenolic composition of extracts was determined with HPLC-DAD, while the antioxidant activity of extracts was evaluated by 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS), and ferric-reducing antioxidant power (FRAP) assays. Bearing in mind that oxidative stress is closely linked to neurodegeneration, the antineurodegenerative potential of the extracts was assessed by the inhibition of acetycholineserase (AChE) and tyrosinase (TYR) activities. The extracts of traditional varieties, particularly peel extracts, had a high content of phenolics, as well as significant antioxidant and moderate antineurodegenerative potential, compared to the commercial variety. The highest contents of total flavonoids and individual compounds, such as arbutin and chlorogenic acid, as well as the strongest antioxidant and TYR inhibitory activities were reported for the ‘Takiša’ peel extract. The performed analyses have revealed that fruits of traditional Serbian pear varieties are rich in bioactive components and could be used as functional food and for possible nutraceutical applications, to prevent diseases induced by oxidative stress.http://journal.pan.olsztyn.pl/Phenolic-Composition-and-Antioxidant-and-Antineurodegenerative-Potential-of-Methanolic,138320,0,2.htmlpear fruittraditional varietiesmethanolic extracts phenolic compositionantioxidant activityantineurodegenerative activity |
| spellingShingle | Aleksandra Savić Ana Alimpić Aradski Jelena Živković Katarina Šavikin Snežana Jarić Petar D. Marin Sonja Duletić-Laušević Phenolic Composition, and Antioxidant and Antineurodegenerative Potential of Methanolic Extracts of Fruit Peel and Flesh of Pear Varieties from Serbia Polish Journal of Food and Nutrition Sciences pear fruit traditional varieties methanolic extracts phenolic composition antioxidant activity antineurodegenerative activity |
| title | Phenolic Composition, and Antioxidant and Antineurodegenerative Potential of Methanolic Extracts of Fruit Peel and Flesh of Pear Varieties from Serbia |
| title_full | Phenolic Composition, and Antioxidant and Antineurodegenerative Potential of Methanolic Extracts of Fruit Peel and Flesh of Pear Varieties from Serbia |
| title_fullStr | Phenolic Composition, and Antioxidant and Antineurodegenerative Potential of Methanolic Extracts of Fruit Peel and Flesh of Pear Varieties from Serbia |
| title_full_unstemmed | Phenolic Composition, and Antioxidant and Antineurodegenerative Potential of Methanolic Extracts of Fruit Peel and Flesh of Pear Varieties from Serbia |
| title_short | Phenolic Composition, and Antioxidant and Antineurodegenerative Potential of Methanolic Extracts of Fruit Peel and Flesh of Pear Varieties from Serbia |
| title_sort | phenolic composition and antioxidant and antineurodegenerative potential of methanolic extracts of fruit peel and flesh of pear varieties from serbia |
| topic | pear fruit traditional varieties methanolic extracts phenolic composition antioxidant activity antineurodegenerative activity |
| url | http://journal.pan.olsztyn.pl/Phenolic-Composition-and-Antioxidant-and-Antineurodegenerative-Potential-of-Methanolic,138320,0,2.html |
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