Streptococcus pneumoniae Coinfection in COVID-19: A Series of Three Cases

Bacterial coinfections are not uncommon with respiratory viral pathogens. These coinfections can add to significant mortality and morbidity. We are currently dealing with the SARS-CoV-2 pandemic, which has affected over 15 million people globally with over half a million deaths. Previous respiratory...

Full description

Saved in:
Bibliographic Details
Main Authors: Chaitanya Pal, Paulina Przydzial, Ogechukwu Chika-Nwosuh, Shrey Shah, Pratik Patel, Nikhil Madan
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Pulmonology
Online Access:http://dx.doi.org/10.1155/2020/8849068
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832550905347571712
author Chaitanya Pal
Paulina Przydzial
Ogechukwu Chika-Nwosuh
Shrey Shah
Pratik Patel
Nikhil Madan
author_facet Chaitanya Pal
Paulina Przydzial
Ogechukwu Chika-Nwosuh
Shrey Shah
Pratik Patel
Nikhil Madan
author_sort Chaitanya Pal
collection DOAJ
description Bacterial coinfections are not uncommon with respiratory viral pathogens. These coinfections can add to significant mortality and morbidity. We are currently dealing with the SARS-CoV-2 pandemic, which has affected over 15 million people globally with over half a million deaths. Previous respiratory viral pandemics have taught us that bacterial coinfections can lead to higher mortality and morbidity. However, there is limited literature on the current SARS-CoV-2 pandemic and associated coinfections, which reported infection rates varying between 1% and 8% based on various cross-sectional studies. In one meta-analysis of coinfections in COVID-19, rates of Streptococcus pneumoniae coinfections have been negligible when compared to previous influenza pandemics. Current literature does not favor the use of empiric, broad-spectrum antibiotics in confirmed SARS-CoV-2 infections. We present three cases of confirmed SARS-CoV-2 infections complicated by Streptococcus pneumoniae coinfection. These cases demonstrate the importance of concomitant testing for common pathogens despite the need for antimicrobial stewardship.
format Article
id doaj-art-5b41cac8a2c843e0926c7fa3f8f0bc9f
institution Kabale University
issn 2090-6846
2090-6854
language English
publishDate 2020-01-01
publisher Wiley
record_format Article
series Case Reports in Pulmonology
spelling doaj-art-5b41cac8a2c843e0926c7fa3f8f0bc9f2025-02-03T06:05:29ZengWileyCase Reports in Pulmonology2090-68462090-68542020-01-01202010.1155/2020/88490688849068Streptococcus pneumoniae Coinfection in COVID-19: A Series of Three CasesChaitanya Pal0Paulina Przydzial1Ogechukwu Chika-Nwosuh2Shrey Shah3Pratik Patel4Nikhil Madan5Department of Medicine, Newark Beth Israel Medical Center, New Jersey 07112, USADepartment of Medicine, Newark Beth Israel Medical Center, New Jersey 07112, USADivision of Pulmonary and Critical Care Medicine, Department of Medicine, Newark Beth Israel Medical Center, New Jersey 07112, USADivision of Pulmonary and Critical Care Medicine, Department of Medicine, Newark Beth Israel Medical Center, New Jersey 07112, USADivision of Pulmonary and Critical Care Medicine, Department of Medicine, Newark Beth Israel Medical Center, New Jersey 07112, USADivision of Pulmonary and Critical Care Medicine, Department of Medicine, Newark Beth Israel Medical Center, New Jersey 07112, USABacterial coinfections are not uncommon with respiratory viral pathogens. These coinfections can add to significant mortality and morbidity. We are currently dealing with the SARS-CoV-2 pandemic, which has affected over 15 million people globally with over half a million deaths. Previous respiratory viral pandemics have taught us that bacterial coinfections can lead to higher mortality and morbidity. However, there is limited literature on the current SARS-CoV-2 pandemic and associated coinfections, which reported infection rates varying between 1% and 8% based on various cross-sectional studies. In one meta-analysis of coinfections in COVID-19, rates of Streptococcus pneumoniae coinfections have been negligible when compared to previous influenza pandemics. Current literature does not favor the use of empiric, broad-spectrum antibiotics in confirmed SARS-CoV-2 infections. We present three cases of confirmed SARS-CoV-2 infections complicated by Streptococcus pneumoniae coinfection. These cases demonstrate the importance of concomitant testing for common pathogens despite the need for antimicrobial stewardship.http://dx.doi.org/10.1155/2020/8849068
spellingShingle Chaitanya Pal
Paulina Przydzial
Ogechukwu Chika-Nwosuh
Shrey Shah
Pratik Patel
Nikhil Madan
Streptococcus pneumoniae Coinfection in COVID-19: A Series of Three Cases
Case Reports in Pulmonology
title Streptococcus pneumoniae Coinfection in COVID-19: A Series of Three Cases
title_full Streptococcus pneumoniae Coinfection in COVID-19: A Series of Three Cases
title_fullStr Streptococcus pneumoniae Coinfection in COVID-19: A Series of Three Cases
title_full_unstemmed Streptococcus pneumoniae Coinfection in COVID-19: A Series of Three Cases
title_short Streptococcus pneumoniae Coinfection in COVID-19: A Series of Three Cases
title_sort streptococcus pneumoniae coinfection in covid 19 a series of three cases
url http://dx.doi.org/10.1155/2020/8849068
work_keys_str_mv AT chaitanyapal streptococcuspneumoniaecoinfectionincovid19aseriesofthreecases
AT paulinaprzydzial streptococcuspneumoniaecoinfectionincovid19aseriesofthreecases
AT ogechukwuchikanwosuh streptococcuspneumoniaecoinfectionincovid19aseriesofthreecases
AT shreyshah streptococcuspneumoniaecoinfectionincovid19aseriesofthreecases
AT pratikpatel streptococcuspneumoniaecoinfectionincovid19aseriesofthreecases
AT nikhilmadan streptococcuspneumoniaecoinfectionincovid19aseriesofthreecases