Hybrid Carcinoma of the Larynx: A Case Report (Adenoid Cystic and Adenocarcinoma) and Review of the Literature
Introduction. The nonsquamous carcinomas of the larynx are considered rare with the majority of malignant tumors in this area, reaching the rate of 95%, to be squamous cell neoplasms. Case Report. The case refers to a 53-year-old man that presented with symptomatology of motor nerve disease. During...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Otolaryngology |
| Online Access: | http://dx.doi.org/10.1155/2013/385405 |
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| author | Ilias Karasmanis John K. Goudakos Iosif Vital Thomas Zarampoukas Victor Vital Konstantinos Markou |
| author_facet | Ilias Karasmanis John K. Goudakos Iosif Vital Thomas Zarampoukas Victor Vital Konstantinos Markou |
| author_sort | Ilias Karasmanis |
| collection | DOAJ |
| description | Introduction. The nonsquamous carcinomas of the larynx are considered rare with the majority of malignant tumors in this area, reaching the rate of 95%, to be squamous cell neoplasms. Case Report. The case refers to a 53-year-old man that presented with symptomatology of motor nerve disease. During the evaluation of the neurologic disease, a subglottic mass of the larynx was revealed accidentally in the imaging examination. Under general anesthesia, we performed direct laryngoscopy and biopsy of the mass. The histopathologic examination revealed a hybrid carcinoma coexistence of two different carcinomas, an adenoid cystic carcinoma and an adenocarcinoma, not otherwise specified with poor differentiation. Regarding the therapeutic plan, the mass was considered inoperable due to its expansion to trachea and the patient received radiotherapy. Conclusions. Both the adenocarcinoma and adenoid cystic carcinoma are extremely rare types of malignant tumors in the larynx. The special interest of the present case is the coexistence of these two rare tumors in the same region of the larynx, being a hybrid tumor of the salivary glands in the larynx, which is the second reported case, based on our systematic literature review. |
| format | Article |
| id | doaj-art-5b344d6f6e664450b2c82195f565ab67 |
| institution | Kabale University |
| issn | 2090-6765 2090-6773 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Otolaryngology |
| spelling | doaj-art-5b344d6f6e664450b2c82195f565ab672025-02-03T06:07:14ZengWileyCase Reports in Otolaryngology2090-67652090-67732013-01-01201310.1155/2013/385405385405Hybrid Carcinoma of the Larynx: A Case Report (Adenoid Cystic and Adenocarcinoma) and Review of the LiteratureIlias Karasmanis0John K. Goudakos1Iosif Vital2Thomas Zarampoukas3Victor Vital4Konstantinos Markou5Department of Otorhinolaryngology, Head and Neck Surgery, Ippokratio Hospital, Konstantinoupoleos 49, 54642 Thessaloniki, Greece1st Department of Otorhinolaryngology, Head and Neck Surgery, AHEPA University Hospital, Aristotle University of Thessaloniki, 1 Stilponos Kyriakidi Street, 54006 Thessaloniki, Greece1st Department of Otorhinolaryngology, Head and Neck Surgery, AHEPA University Hospital, Aristotle University of Thessaloniki, 1 Stilponos Kyriakidi Street, 54006 Thessaloniki, GreeceDepartment of Pathology, Medical School, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece1st Department of Otorhinolaryngology, Head and Neck Surgery, AHEPA University Hospital, Aristotle University of Thessaloniki, 1 Stilponos Kyriakidi Street, 54006 Thessaloniki, Greece1st Department of Otorhinolaryngology, Head and Neck Surgery, AHEPA University Hospital, Aristotle University of Thessaloniki, 1 Stilponos Kyriakidi Street, 54006 Thessaloniki, GreeceIntroduction. The nonsquamous carcinomas of the larynx are considered rare with the majority of malignant tumors in this area, reaching the rate of 95%, to be squamous cell neoplasms. Case Report. The case refers to a 53-year-old man that presented with symptomatology of motor nerve disease. During the evaluation of the neurologic disease, a subglottic mass of the larynx was revealed accidentally in the imaging examination. Under general anesthesia, we performed direct laryngoscopy and biopsy of the mass. The histopathologic examination revealed a hybrid carcinoma coexistence of two different carcinomas, an adenoid cystic carcinoma and an adenocarcinoma, not otherwise specified with poor differentiation. Regarding the therapeutic plan, the mass was considered inoperable due to its expansion to trachea and the patient received radiotherapy. Conclusions. Both the adenocarcinoma and adenoid cystic carcinoma are extremely rare types of malignant tumors in the larynx. The special interest of the present case is the coexistence of these two rare tumors in the same region of the larynx, being a hybrid tumor of the salivary glands in the larynx, which is the second reported case, based on our systematic literature review.http://dx.doi.org/10.1155/2013/385405 |
| spellingShingle | Ilias Karasmanis John K. Goudakos Iosif Vital Thomas Zarampoukas Victor Vital Konstantinos Markou Hybrid Carcinoma of the Larynx: A Case Report (Adenoid Cystic and Adenocarcinoma) and Review of the Literature Case Reports in Otolaryngology |
| title | Hybrid Carcinoma of the Larynx: A Case Report (Adenoid Cystic and Adenocarcinoma) and Review of the Literature |
| title_full | Hybrid Carcinoma of the Larynx: A Case Report (Adenoid Cystic and Adenocarcinoma) and Review of the Literature |
| title_fullStr | Hybrid Carcinoma of the Larynx: A Case Report (Adenoid Cystic and Adenocarcinoma) and Review of the Literature |
| title_full_unstemmed | Hybrid Carcinoma of the Larynx: A Case Report (Adenoid Cystic and Adenocarcinoma) and Review of the Literature |
| title_short | Hybrid Carcinoma of the Larynx: A Case Report (Adenoid Cystic and Adenocarcinoma) and Review of the Literature |
| title_sort | hybrid carcinoma of the larynx a case report adenoid cystic and adenocarcinoma and review of the literature |
| url | http://dx.doi.org/10.1155/2013/385405 |
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