Relative anterior spinal overgrowth in mild and moderate adolescent idiopathic scoliosis: a retrospective study
Abstract To determine whether relative anterior spinal overgrowth (RASO) occurs regardless of scoliosis segments and severity, and to explore the pattern of vertebral body height changes in adolescent idiopathic scoliosis (AIS). A total of 125 AIS and 179 non-scoliotic adolescents were enrolled. The...
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Nature Portfolio
2025-01-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-025-86912-0 |
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| author | Haoyang Zhang Xin Ye Hongjiao Wu Yi Shen Yingsen Pan Xiaoming Ying Jiaying He |
| author_facet | Haoyang Zhang Xin Ye Hongjiao Wu Yi Shen Yingsen Pan Xiaoming Ying Jiaying He |
| author_sort | Haoyang Zhang |
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| description | Abstract To determine whether relative anterior spinal overgrowth (RASO) occurs regardless of scoliosis segments and severity, and to explore the pattern of vertebral body height changes in adolescent idiopathic scoliosis (AIS). A total of 125 AIS and 179 non-scoliotic adolescents were enrolled. The anterior vertebral body height (VBHa) and posterior vertebral body height (VBHp) were measured on lateral spine radiographs, and the VBHa/VBHp ratio was calculated. The ratios were compared between the two groups and across scoliosis segments in the AIS group. The correlation between scoliosis severity and vertebral ratios, as well as the relationship between the apex vertebra’s ratio and Cobb angle, was analyzed. Results showed that the VBHa/VBHp ratios were higher in the AIS group than the control group from T6 to L5 (P < 0.001), with increasing ratios from T7 to T10 and L1 to L5. No significant differences were found across scoliosis segments. Pearson analysis showed positive correlations between scoliosis severity and ratios at T7, T8, and T11 (P < 0.05), and a negative correlation at L5 (P < 0.05). No correlation was found between the apex vertebra’s ratio and the Cobb angle. In conclusion, RASO is common in mild to moderate AIS and may help maintain spinal function. |
| format | Article |
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| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-01-01 |
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| spelling | doaj-art-5af1a9e2017646bb8d2500fb69a132142025-01-26T12:23:40ZengNature PortfolioScientific Reports2045-23222025-01-011511910.1038/s41598-025-86912-0Relative anterior spinal overgrowth in mild and moderate adolescent idiopathic scoliosis: a retrospective studyHaoyang Zhang0Xin Ye1Hongjiao Wu2Yi Shen3Yingsen Pan4Xiaoming Ying5Jiaying He6Tuina department, Hangzhou Hospital of Traditional Chinese Medicine Hangzhou TCM Affiliated to Zhejiang Chinese Medicine UniversityTuina department, The 3rd affiliated hospital of Zhejiang Chinese Medical UniversityTuina department, Hangzhou Hospital of Traditional Chinese Medicine Hangzhou TCM Affiliated to Zhejiang Chinese Medicine UniversityThe 3rd clinical medical college of Zhejiang Chinese Medical UniversityThe 3rd clinical medical college of Zhejiang Chinese Medical UniversityTuina department, The 3rd affiliated hospital of Zhejiang Chinese Medical UniversityTuina department, Hangzhou Hospital of Traditional Chinese Medicine Hangzhou TCM Affiliated to Zhejiang Chinese Medicine UniversityAbstract To determine whether relative anterior spinal overgrowth (RASO) occurs regardless of scoliosis segments and severity, and to explore the pattern of vertebral body height changes in adolescent idiopathic scoliosis (AIS). A total of 125 AIS and 179 non-scoliotic adolescents were enrolled. The anterior vertebral body height (VBHa) and posterior vertebral body height (VBHp) were measured on lateral spine radiographs, and the VBHa/VBHp ratio was calculated. The ratios were compared between the two groups and across scoliosis segments in the AIS group. The correlation between scoliosis severity and vertebral ratios, as well as the relationship between the apex vertebra’s ratio and Cobb angle, was analyzed. Results showed that the VBHa/VBHp ratios were higher in the AIS group than the control group from T6 to L5 (P < 0.001), with increasing ratios from T7 to T10 and L1 to L5. No significant differences were found across scoliosis segments. Pearson analysis showed positive correlations between scoliosis severity and ratios at T7, T8, and T11 (P < 0.05), and a negative correlation at L5 (P < 0.05). No correlation was found between the apex vertebra’s ratio and the Cobb angle. In conclusion, RASO is common in mild to moderate AIS and may help maintain spinal function.https://doi.org/10.1038/s41598-025-86912-0 |
| spellingShingle | Haoyang Zhang Xin Ye Hongjiao Wu Yi Shen Yingsen Pan Xiaoming Ying Jiaying He Relative anterior spinal overgrowth in mild and moderate adolescent idiopathic scoliosis: a retrospective study Scientific Reports |
| title | Relative anterior spinal overgrowth in mild and moderate adolescent idiopathic scoliosis: a retrospective study |
| title_full | Relative anterior spinal overgrowth in mild and moderate adolescent idiopathic scoliosis: a retrospective study |
| title_fullStr | Relative anterior spinal overgrowth in mild and moderate adolescent idiopathic scoliosis: a retrospective study |
| title_full_unstemmed | Relative anterior spinal overgrowth in mild and moderate adolescent idiopathic scoliosis: a retrospective study |
| title_short | Relative anterior spinal overgrowth in mild and moderate adolescent idiopathic scoliosis: a retrospective study |
| title_sort | relative anterior spinal overgrowth in mild and moderate adolescent idiopathic scoliosis a retrospective study |
| url | https://doi.org/10.1038/s41598-025-86912-0 |
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