Indoxyl Sulfate-Induced Oxidative Stress, Mitochondrial Dysfunction, and Impaired Biogenesis Are Partly Protected by Vitamin C and N-Acetylcysteine
Indoxyl sulfate (IS) contributes to oxidative stress and endothelial dysfunction in chronic kidney disease patients. However, the role of mitochondria in IS-induced oxidative stress is not very clear. In this study, we examined whether mitochondria play a pivotal role in modulating the effects of an...
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Main Authors: | Wen-Chin Lee, Lung-Chih Li, Jin-Bor Chen, Hsueh-Wei Chang |
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Format: | Article |
Language: | English |
Published: |
Wiley
2015-01-01
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Series: | The Scientific World Journal |
Online Access: | http://dx.doi.org/10.1155/2015/620826 |
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