Can the monocyte/HDL ratio predict ear effusion in adenoid vegetation patients?
Abstract Background Since monocytes secrete cytokines, high monocyte counts may indicate subclinical inflammation. HDL-C, a significant component of total cholesterol, may reduce inflammation. Objectives This study investigated whether the monocyte/HDL ratio (MHR) could be an independent predictive...
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SpringerOpen
2025-01-01
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| Series: | The Egyptian Journal of Otolaryngology |
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| Online Access: | https://doi.org/10.1186/s43163-025-00759-w |
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| author | Elif Kaya Çelik Fatih Öner |
| author_facet | Elif Kaya Çelik Fatih Öner |
| author_sort | Elif Kaya Çelik |
| collection | DOAJ |
| description | Abstract Background Since monocytes secrete cytokines, high monocyte counts may indicate subclinical inflammation. HDL-C, a significant component of total cholesterol, may reduce inflammation. Objectives This study investigated whether the monocyte/HDL ratio (MHR) could be an independent predictive marker in patients with adenoid vegetation, both with and without otitis media with effusion (OME). Methods This cross-sectional study included patients diagnosed with adenoid vegetation, with or without OME, who underwent surgery. The groups consisted of patients who underwent adenoidectomy alone for adenoid vegetation and those who underwent adenoidectomy + ventilation tube for adenoid vegetation with OME (Group 2). Monocyte counts, HDL-C levels, and MHR values were calculated for both groups. Results The mean age of Group 1 was 6.95 ± 2.77 years, while Group 2 had a mean age of 6.61 ± 2.98 years. No significant difference was found in monocyte count or percentage between the groups. The HDL-C ratios were lower in Group 2, which OME accompanied, and the difference between the groups was significant (p: 0.027). The MHR was not significantly different between Groups 1 and 2, with values of 10.47 (4.22–29.23) and 12.29 (5.43–99.6), respectively. Conclusion Reduced MHR ratios may indicate elevated inflammatory levels in the body and may be linked to certain medical conditions. However, we found no significant difference in the parameters’ ability to predict OME in children with adenoid vegetation. Therefore, a simple, low-cost marker to predict middle ear effusion in children is needed. |
| format | Article |
| id | doaj-art-5a7b433c63294603b8995445731c9de1 |
| institution | Kabale University |
| issn | 2090-8539 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Journal of Otolaryngology |
| spelling | doaj-art-5a7b433c63294603b8995445731c9de12025-01-26T12:12:28ZengSpringerOpenThe Egyptian Journal of Otolaryngology2090-85392025-01-014111610.1186/s43163-025-00759-wCan the monocyte/HDL ratio predict ear effusion in adenoid vegetation patients?Elif Kaya Çelik0Fatih Öner1Faculty of Medicine, Department of Otolaryngology Head and Neck Surgery, Tokat Gaziosmanpaşa UniversityFaculty of Medicine, Department of Otorhinolaryngology, Kastamonu UniversityAbstract Background Since monocytes secrete cytokines, high monocyte counts may indicate subclinical inflammation. HDL-C, a significant component of total cholesterol, may reduce inflammation. Objectives This study investigated whether the monocyte/HDL ratio (MHR) could be an independent predictive marker in patients with adenoid vegetation, both with and without otitis media with effusion (OME). Methods This cross-sectional study included patients diagnosed with adenoid vegetation, with or without OME, who underwent surgery. The groups consisted of patients who underwent adenoidectomy alone for adenoid vegetation and those who underwent adenoidectomy + ventilation tube for adenoid vegetation with OME (Group 2). Monocyte counts, HDL-C levels, and MHR values were calculated for both groups. Results The mean age of Group 1 was 6.95 ± 2.77 years, while Group 2 had a mean age of 6.61 ± 2.98 years. No significant difference was found in monocyte count or percentage between the groups. The HDL-C ratios were lower in Group 2, which OME accompanied, and the difference between the groups was significant (p: 0.027). The MHR was not significantly different between Groups 1 and 2, with values of 10.47 (4.22–29.23) and 12.29 (5.43–99.6), respectively. Conclusion Reduced MHR ratios may indicate elevated inflammatory levels in the body and may be linked to certain medical conditions. However, we found no significant difference in the parameters’ ability to predict OME in children with adenoid vegetation. Therefore, a simple, low-cost marker to predict middle ear effusion in children is needed.https://doi.org/10.1186/s43163-025-00759-wAdenoid vegetationOtitis media with effusionHigh-density lipoproteinMonocyteMonocyte/HDL ratio |
| spellingShingle | Elif Kaya Çelik Fatih Öner Can the monocyte/HDL ratio predict ear effusion in adenoid vegetation patients? The Egyptian Journal of Otolaryngology Adenoid vegetation Otitis media with effusion High-density lipoprotein Monocyte Monocyte/HDL ratio |
| title | Can the monocyte/HDL ratio predict ear effusion in adenoid vegetation patients? |
| title_full | Can the monocyte/HDL ratio predict ear effusion in adenoid vegetation patients? |
| title_fullStr | Can the monocyte/HDL ratio predict ear effusion in adenoid vegetation patients? |
| title_full_unstemmed | Can the monocyte/HDL ratio predict ear effusion in adenoid vegetation patients? |
| title_short | Can the monocyte/HDL ratio predict ear effusion in adenoid vegetation patients? |
| title_sort | can the monocyte hdl ratio predict ear effusion in adenoid vegetation patients |
| topic | Adenoid vegetation Otitis media with effusion High-density lipoprotein Monocyte Monocyte/HDL ratio |
| url | https://doi.org/10.1186/s43163-025-00759-w |
| work_keys_str_mv | AT elifkayacelik canthemonocytehdlratiopredicteareffusioninadenoidvegetationpatients AT fatihoner canthemonocytehdlratiopredicteareffusioninadenoidvegetationpatients |